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Molecular basis of C-S bond cleavage in the glycyl radical enzyme isethionate sulfite-lyase.
Dawson, Christopher D; Irwin, Stephania M; Backman, Lindsey R F; Le, Chip; Wang, Jennifer X; Vennelakanti, Vyshnavi; Yang, Zhongyue; Kulik, Heather J; Drennan, Catherine L; Balskus, Emily P.
Affiliation
  • Dawson CD; Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
  • Irwin SM; Department of Chemistry and Chemical Biology, Harvard University, 12 Oxford Street, Cambridge, MA 02138, USA.
  • Backman LRF; Department of Chemistry, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
  • Le C; Department of Chemistry and Chemical Biology, Harvard University, 12 Oxford Street, Cambridge, MA 02138, USA.
  • Wang JX; Harvard Center for Mass Spectrometry, Faculty of Arts and Sciences Division of Science, Harvard University, 52 Oxford Street, Cambridge, MA 02138, USA.
  • Vennelakanti V; Department of Chemistry, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
  • Yang Z; Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
  • Kulik HJ; Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA. Electronic address: hjkulik@mit.edu.
  • Drennan CL; Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; Department of Chemistry, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; Howard Hughes Medical Institute, Massachusetts Institute of Technology, Cambridge, MA 02139, USA. Electronic address: cdre
  • Balskus EP; Department of Chemistry and Chemical Biology, Harvard University, 12 Oxford Street, Cambridge, MA 02138, USA; Broad Institute, Cambridge, MA 02139, USA. Electronic address: balskus@chemistry.harvard.edu.
Cell Chem Biol ; 28(9): 1333-1346.e7, 2021 09 16.
Article in En | MEDLINE | ID: mdl-33773110
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Sulfur / Carbon / Lyases Language: En Journal: Cell Chem Biol Year: 2021 Document type: Article Affiliation country: Estados Unidos
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Sulfur / Carbon / Lyases Language: En Journal: Cell Chem Biol Year: 2021 Document type: Article Affiliation country: Estados Unidos