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In vitro chronic glycation induces AGEs accumulation reducing insulin-stimulated glucose uptake and increasing GLP1R in adipocytes.
Chilelli, Nino-Cristiano; Faggian, Alessia; Favaretto, Francesca; Milan, Gabriella; Compagnin, Chiara; Dassie, Francesca; Bettini, Silvia; Roverso, Marco; Seraglia, Roberta; Lapolla, Annunziata; Vettor, Roberto.
Affiliation
  • Chilelli NC; Department of Medicine, University of Padua, Diabetology and Dietetics, Padua, Italy.
  • Faggian A; Department of Medicine, University of Padua, Internal Medicine 3, Padua, Italy.
  • Favaretto F; Department of Medicine, University of Padua, Internal Medicine 3, Padua, Italy.
  • Milan G; Department of Medicine, University of Padua, Internal Medicine 3, Padua, Italy.
  • Compagnin C; Department of Medicine, University of Padua, Internal Medicine 3, Padua, Italy.
  • Dassie F; Department of Medicine, University of Padua, Internal Medicine 3, Padua, Italy.
  • Bettini S; Department of Medicine, University of Padua, Internal Medicine 3, Padua, Italy.
  • Roverso M; Department of Chemical Sciences, University of Padua, Padua, Italy.
  • Seraglia R; Consiglio Nazionale delle Ricerche-Istituto di Chimica della Materia Condensata e di Tecnologie per l'Energia (CNR-ICMATE), Padua, Italy.
  • Lapolla A; Department of Medicine, University of Padua, Diabetology and Dietetics, Padua, Italy.
  • Vettor R; Department of Medicine, University of Padua, Internal Medicine 3, Padua, Italy.
Am J Physiol Endocrinol Metab ; 320(5): E976-E988, 2021 05 01.
Article in En | MEDLINE | ID: mdl-33779307
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Glycation End Products, Advanced / Adipocytes / Glucagon-Like Peptide-1 Receptor / Glucose / Insulin Limits: Animals / Humans Language: En Journal: Am J Physiol Endocrinol Metab Journal subject: ENDOCRINOLOGIA / FISIOLOGIA / METABOLISMO Year: 2021 Document type: Article Affiliation country: Italia
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Glycation End Products, Advanced / Adipocytes / Glucagon-Like Peptide-1 Receptor / Glucose / Insulin Limits: Animals / Humans Language: En Journal: Am J Physiol Endocrinol Metab Journal subject: ENDOCRINOLOGIA / FISIOLOGIA / METABOLISMO Year: 2021 Document type: Article Affiliation country: Italia