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3D iPSC modeling of the retinal pigment epithelium-choriocapillaris complex identifies factors involved in the pathology of macular degeneration.
Manian, Kannan V; Galloway, Chad A; Dalvi, Sonal; Emanuel, Anthony A; Mereness, Jared A; Black, Whitney; Winschel, Lauren; Soto, Celia; Li, Yiming; Song, Yuanhui; DeMaria, William; Kumar, Akhilesh; Slukvin, Igor; Schwartz, Michael P; Murphy, William L; Anand-Apte, Bela; Chung, Mina; Benoit, Danielle S W; Singh, Ruchira.
Affiliation
  • Manian KV; Department of Ophthalmology, University of Rochester, Rochester, NY 14620, USA; Department of Biomedical Genetics, University of Rochester, Rochester, NY 14620, USA.
  • Galloway CA; Department of Ophthalmology, University of Rochester, Rochester, NY 14620, USA; Department of Biomedical Genetics, University of Rochester, Rochester, NY 14620, USA; Department of Pathology and Laboratory Medicine, University of Rochester, Rochester, NY 14620, USA.
  • Dalvi S; Department of Ophthalmology, University of Rochester, Rochester, NY 14620, USA; Department of Biomedical Genetics, University of Rochester, Rochester, NY 14620, USA.
  • Emanuel AA; Department of Ophthalmology, University of Rochester, Rochester, NY 14620, USA; Department of Biomedical Genetics, University of Rochester, Rochester, NY 14620, USA.
  • Mereness JA; Department of Biomedical Engineering, Robert B. Goergen Hall, University of Rochester, Rochester, NY 14627, USA; Department of Orthopedics and Center for Musculoskeletal Research, University of Rochester, Rochester, NY 14642, USA; Center for Oral Biology, University of Rochester, Rochester, NY 14642
  • Black W; Department of Ophthalmology, University of Rochester, Rochester, NY 14620, USA; Department of Biomedical Genetics, University of Rochester, Rochester, NY 14620, USA.
  • Winschel L; Department of Ophthalmology, University of Rochester, Rochester, NY 14620, USA; Department of Biomedical Genetics, University of Rochester, Rochester, NY 14620, USA.
  • Soto C; Department of Ophthalmology, University of Rochester, Rochester, NY 14620, USA; Department of Biomedical Genetics, University of Rochester, Rochester, NY 14620, USA.
  • Li Y; Department of Biomedical Engineering, Robert B. Goergen Hall, University of Rochester, Rochester, NY 14627, USA.
  • Song Y; Department of Biomedical Engineering, Robert B. Goergen Hall, University of Rochester, Rochester, NY 14627, USA.
  • DeMaria W; Department of Biomedical Engineering, Robert B. Goergen Hall, University of Rochester, Rochester, NY 14627, USA.
  • Kumar A; Wisconsin National Primate Research Center, University of Wisconsin, Madison, WI 53715, USA.
  • Slukvin I; Wisconsin National Primate Research Center, University of Wisconsin, Madison, WI 53715, USA; Department of Cell and Regenerative Biology, University of Wisconsin School of Medicine and Public Health, Madison, WI 53715, USA.
  • Schwartz MP; NSF Center for Sustainable Nanotechnology, Department of Chemistry, University of Wisconsin, Madison, WI 53706, USA; Department of Biomedical Engineering, University of Wisconsin, Madison, WI 53715, USA.
  • Murphy WL; Department of Biomedical Engineering, University of Wisconsin, Madison, WI 53715, USA; Department of Orthopedics and Rehabilitation, University of Wisconsin, Madison, WI 53715, USA.
  • Anand-Apte B; Department of Ophthalmic Research, Cole Eye Institute and Lerner Research Institute, Cleveland Clinic, Cleveland, OH 44195, USA.
  • Chung M; Department of Ophthalmology, University of Rochester, Rochester, NY 14620, USA; Center for Visual Science, University of Rochester, Rochester, NY 14620, USA.
  • Benoit DSW; Department of Biomedical Genetics, University of Rochester, Rochester, NY 14620, USA; Department of Pathology and Laboratory Medicine, University of Rochester, Rochester, NY 14620, USA; Department of Biomedical Engineering, Robert B. Goergen Hall, University of Rochester, Rochester, NY 14627, USA; D
  • Singh R; Department of Ophthalmology, University of Rochester, Rochester, NY 14620, USA; Department of Biomedical Genetics, University of Rochester, Rochester, NY 14620, USA; Department of Orthopedics and Center for Musculoskeletal Research, University of Rochester, Rochester, NY 14642, USA; Center for Visua
Cell Stem Cell ; 28(5): 846-862.e8, 2021 05 06.
Article in En | MEDLINE | ID: mdl-33784497
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Choroid Diseases / Induced Pluripotent Stem Cells / Macular Degeneration Type of study: Prognostic_studies Limits: Humans Language: En Journal: Cell Stem Cell Year: 2021 Document type: Article Affiliation country: Estados Unidos Country of publication: Estados Unidos
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Choroid Diseases / Induced Pluripotent Stem Cells / Macular Degeneration Type of study: Prognostic_studies Limits: Humans Language: En Journal: Cell Stem Cell Year: 2021 Document type: Article Affiliation country: Estados Unidos Country of publication: Estados Unidos