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Serotonin and chronic hypoxic pulmonary hypertension activate a NADPH oxidase 4 and TRPM2 dependent pathway for pulmonary arterial smooth muscle cell proliferation and migration.
Song, Jia-Lin; Zheng, Si-Yi; He, Rui-Lan; Gui, Long-Xin; Lin, Mo-Jun; Sham, James S K.
Affiliation
  • Song JL; Key Laboratory of Fujian Province Universities on Ion Channel and Signal Transduction in Cardiovascular Diseases, Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Fujian Medical University, Fuzhou, Fujian Province, PR China.
  • Zheng SY; Key Laboratory of Fujian Province Universities on Ion Channel and Signal Transduction in Cardiovascular Diseases, Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Fujian Medical University, Fuzhou, Fujian Province, PR China.
  • He RL; Key Laboratory of Fujian Province Universities on Ion Channel and Signal Transduction in Cardiovascular Diseases, Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Fujian Medical University, Fuzhou, Fujian Province, PR China.
  • Gui LX; Key Laboratory of Fujian Province Universities on Ion Channel and Signal Transduction in Cardiovascular Diseases, Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Fujian Medical University, Fuzhou, Fujian Province, PR China.
  • Lin MJ; Key Laboratory of Fujian Province Universities on Ion Channel and Signal Transduction in Cardiovascular Diseases, Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Fujian Medical University, Fuzhou, Fujian Province, PR China. Electronic address: mjlin@mail.fjmu.edu.cn.
  • Sham JSK; Division of Pulmonary and Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA. Electronic address: jsks@jhmi.edu.
Vascul Pharmacol ; 138: 106860, 2021 06.
Article in En | MEDLINE | ID: mdl-33794383
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Serotonin / Cell Movement / Myocytes, Smooth Muscle / Cell Proliferation / TRPM Cation Channels / NADPH Oxidase 4 / Pulmonary Arterial Hypertension / Muscle, Smooth, Vascular Type of study: Etiology_studies Limits: Animals Language: En Journal: Vascul Pharmacol Journal subject: ANGIOLOGIA / FARMACOLOGIA Year: 2021 Document type: Article Country of publication: Estados Unidos
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Serotonin / Cell Movement / Myocytes, Smooth Muscle / Cell Proliferation / TRPM Cation Channels / NADPH Oxidase 4 / Pulmonary Arterial Hypertension / Muscle, Smooth, Vascular Type of study: Etiology_studies Limits: Animals Language: En Journal: Vascul Pharmacol Journal subject: ANGIOLOGIA / FARMACOLOGIA Year: 2021 Document type: Article Country of publication: Estados Unidos