A Survey on How Ocular Surface Demodex Infestation Interactively Associates with Diabetes Mellitus and Dry Eye Disease.
Acta Parasitol
; 66(3): 1039-1047, 2021 Sep.
Article
in En
| MEDLINE
| ID: mdl-33813654
ABSTRACT
PURPOSE:
Prevention of ocular surface (OS) Demodex infestation plays an important role in OS hygiene and variety of factors may be associated with it, in which diabetes mellitus (DM) or dry eye disease (DED) has caught the attention of most scholars. However, there has been no research on whether there was a potential interaction between DM and DED in the process of OS Demodex infestation. This cross-sectional study was implemented in Zhujiang Hospital of Southern Medical University.METHODS:
Ophthalmologic interviews, questionnaires, and examinations were conducted. Factors including general information, DM status, dry eye condition, etc. were collected to study the correlation of DM and DED on OS Demodex infestation.RESULTS:
After statistical analysis, we found that both DM (P < 0.001) and DED (P = 0.013 < 0.05) are closely associated with OS Demodex infestation. Compared with DED, DM has higher priority association with OS Demodex infestation, and patients with both diseases have a significant higher risk of OS Demodex infestation (R = 0.197, P < 0.001). Meanwhile, age (R = 0.299, P < 0.001) and hypertension (P < 0.05) were also correlated with OS Demodex infestation.CONCLUSION:
This study provides a new evidence-based basis for clinical prevention and management of OS Demodex infestation.Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Dry Eye Syndromes
/
Eye Infections, Parasitic
/
Diabetes Mellitus
/
Eyelashes
/
Mite Infestations
/
Mites
Type of study:
Observational_studies
/
Prevalence_studies
/
Risk_factors_studies
Limits:
Animals
/
Humans
Language:
En
Journal:
Acta Parasitol
Year:
2021
Document type:
Article
Affiliation country:
China