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SHP2-Mediated Inhibition of DNA Repair Contributes to cGAS-STING Activation and Chemotherapeutic Sensitivity in Colon Cancer.
Wei, Bin; Xu, Lingyan; Guo, Wenjie; Wang, Yuanyuan; Wu, Jingjing; Li, Xiaofei; Cai, Xiaomin; Hu, Jinbo; Wang, Meijing; Xu, Qiang; Liu, Wen; Gu, Yanhong.
Affiliation
  • Wei B; Department of Oncology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, P.R. China.
  • Xu L; Department of Oncology, The Affiliated Huaian No. 1 People's Hospital of Nanjing Medical University, Huai'an, P.R. China.
  • Guo W; Department of Oncology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, P.R. China.
  • Wang Y; State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing, P.R. China.
  • Wu J; Department of Oncology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, P.R. China.
  • Li X; Department of Oncology, The Affiliated Huaian No. 1 People's Hospital of Nanjing Medical University, Huai'an, P.R. China.
  • Cai X; Department of Oncology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, P.R. China.
  • Hu J; Department of Oncology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, P.R. China.
  • Wang M; State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing, P.R. China.
  • Xu Q; State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing, P.R. China.
  • Liu W; State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing, P.R. China.
  • Gu Y; State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing, P.R. China. guyhphd@163.com liuwen1849@126.com.
Cancer Res ; 81(12): 3215-3228, 2021 06 15.
Article in En | MEDLINE | ID: mdl-33820798
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Antineoplastic Combined Chemotherapy Protocols / Gene Expression Regulation, Neoplastic / Colonic Neoplasms / DNA Repair / Protein Tyrosine Phosphatase, Non-Receptor Type 11 / Membrane Proteins / Nucleotidyltransferases Type of study: Diagnostic_studies / Prognostic_studies Limits: Animals / Female / Humans Language: En Journal: Cancer Res Year: 2021 Document type: Article Country of publication: Estados Unidos
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Antineoplastic Combined Chemotherapy Protocols / Gene Expression Regulation, Neoplastic / Colonic Neoplasms / DNA Repair / Protein Tyrosine Phosphatase, Non-Receptor Type 11 / Membrane Proteins / Nucleotidyltransferases Type of study: Diagnostic_studies / Prognostic_studies Limits: Animals / Female / Humans Language: En Journal: Cancer Res Year: 2021 Document type: Article Country of publication: Estados Unidos