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Central human B cell tolerance manifests with a distinctive cell phenotype and is enforced via CXCR4 signaling in hu-mice.
Alves da Costa, Thiago; Peterson, Jacob N; Lang, Julie; Shulman, Jeremy; Liang, Xiayuan; Freed, Brian M; Boackle, Susan A; Lauzurica, Pilar; Torres, Raul M; Pelanda, Roberta.
Affiliation
  • Alves da Costa T; Department of Immunology and Microbiology, University of Colorado Anschutz Medical Campus, Aurora, CO 80045.
  • Peterson JN; Department of Immunology and Microbiology, University of Colorado Anschutz Medical Campus, Aurora, CO 80045.
  • Lang J; Department of Immunology and Microbiology, University of Colorado Anschutz Medical Campus, Aurora, CO 80045.
  • Shulman J; Department of Immunology and Microbiology, University of Colorado Anschutz Medical Campus, Aurora, CO 80045.
  • Liang X; Department of Pathology, University of Colorado School of Medicine and Children's Hospital of Colorado, Aurora, CO 80045.
  • Freed BM; Department of Medicine, Division of Allergy and Clinical Immunology, University of Colorado Anschutz Medical Campus, Aurora, CO 80045.
  • Boackle SA; Department of Medicine, Division of Rheumatology, University of Colorado Anschutz Medical Campus, Aurora, CO 80045.
  • Lauzurica P; Department of Immunology, Centro Nacional de Microbiologia, Majadahonda, 28222 Madrid, Spain.
  • Torres RM; Department of Immunology and Microbiology, University of Colorado Anschutz Medical Campus, Aurora, CO 80045.
  • Pelanda R; Department of Immunology and Genomic Medicine, National Jewish Health, Denver, CO 80206.
Proc Natl Acad Sci U S A ; 118(16)2021 04 20.
Article in En | MEDLINE | ID: mdl-33850015
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Receptors, CXCR4 / Precursor Cells, B-Lymphoid / Central Tolerance Type of study: Prognostic_studies Limits: Animals / Female / Humans / Male / Newborn Language: En Journal: Proc Natl Acad Sci U S A Year: 2021 Document type: Article
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Receptors, CXCR4 / Precursor Cells, B-Lymphoid / Central Tolerance Type of study: Prognostic_studies Limits: Animals / Female / Humans / Male / Newborn Language: En Journal: Proc Natl Acad Sci U S A Year: 2021 Document type: Article