Novel Aryl-Substituted Pyrimidones as Inhibitors of 3-Mercaptopyruvate Sulfurtransferase with Antiproliferative Efficacy in Colon Cancer.

Bantzi, Marina; Augsburger, Fiona; Loup, Jérémie; Berset, Yan; Vasilakaki, Sofia; Myrianthopoulos, Vassilios; Mikros, Emmanuel; Szabo, Csaba; Bochet, Christian G

Bantzi, Marina; Augsburger, Fiona; Loup, Jérémie; Berset, Yan; Vasilakaki, Sofia; Myrianthopoulos, Vassilios; Mikros, Emmanuel; Szabo, Csaba; Bochet, Christian G.

Affiliation

Bantzi M; Department of Chemistry, University of Fribourg, 1700 Fribourg, Switzerland.
Augsburger F; Chair of Pharmacology, Faculty of Science and Medicine University of Fribourg, 1700 Fribourg, Switzerland.
Loup J; Chair of Pharmacology, Faculty of Science and Medicine University of Fribourg, 1700 Fribourg, Switzerland.
Berset Y; Department of Chemistry, University of Fribourg, 1700 Fribourg, Switzerland.
Vasilakaki S; Department of Chemistry, University of Fribourg, 1700 Fribourg, Switzerland.
Myrianthopoulos V; Faculty of Pharmacy, Department of Pharmaceutical Chemistry, University of Athens, 15772 Athens, Greece.
Mikros E; Faculty of Pharmacy, Department of Pharmaceutical Chemistry, University of Athens, 15772 Athens, Greece.
Szabo C; Faculty of Pharmacy, Department of Pharmaceutical Chemistry, University of Athens, 15772 Athens, Greece.
Bochet CG; Chair of Pharmacology, Faculty of Science and Medicine University of Fribourg, 1700 Fribourg, Switzerland.

J Med Chem ; 64(9): 6221-6240, 2021 05 13.

Article in En | MEDLINE | ID: mdl-33856792

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyrimidinones / Sulfurtransferases / Colonic Neoplasms / Enzyme Inhibitors Limits: Animals Language: En Journal: J Med Chem Journal subject: QUIMICA Year: 2021 Document type: Article Affiliation country: Suiza Country of publication: Estados Unidos

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