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Activation of von Willebrand factor via mechanical unfolding of its discontinuous autoinhibitory module.
Arce, Nicholas A; Cao, Wenpeng; Brown, Alexander K; Legan, Emily R; Wilson, Moriah S; Xu, Emma-Ruoqi; Berndt, Michael C; Emsley, Jonas; Zhang, X Frank; Li, Renhao.
Affiliation
  • Arce NA; Aflac Cancer and Blood Disorders Center, Children's Healthcare of Atlanta, Department of Pediatrics, Emory University School of Medicine, Atlanta, GA, USA.
  • Cao W; Department of Bioengineering, Department of Mechanical Engineering & Mechanics, Lehigh University, Bethlehem, PA, USA.
  • Brown AK; Biodiscovery Institute, School of Pharmacy, University of Nottingham, Nottingham, UK.
  • Legan ER; Aflac Cancer and Blood Disorders Center, Children's Healthcare of Atlanta, Department of Pediatrics, Emory University School of Medicine, Atlanta, GA, USA.
  • Wilson MS; Aflac Cancer and Blood Disorders Center, Children's Healthcare of Atlanta, Department of Pediatrics, Emory University School of Medicine, Atlanta, GA, USA.
  • Xu ER; Biodiscovery Institute, School of Pharmacy, University of Nottingham, Nottingham, UK.
  • Berndt MC; Faculty of Health Sciences, Curtin University, Perth, WA, Australia.
  • Emsley J; Biodiscovery Institute, School of Pharmacy, University of Nottingham, Nottingham, UK.
  • Zhang XF; Department of Bioengineering, Department of Mechanical Engineering & Mechanics, Lehigh University, Bethlehem, PA, USA. xiz310@lehigh.edu.
  • Li R; Aflac Cancer and Blood Disorders Center, Children's Healthcare of Atlanta, Department of Pediatrics, Emory University School of Medicine, Atlanta, GA, USA. renhao.li@emory.edu.
Nat Commun ; 12(1): 2360, 2021 04 21.
Article in En | MEDLINE | ID: mdl-33883551
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Von Willebrand Factor Type of study: Prognostic_studies Limits: Humans Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2021 Document type: Article Affiliation country: Estados Unidos Country of publication: Reino Unido
Fulltext
Add to My VHL
Print
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Von Willebrand Factor Type of study: Prognostic_studies Limits: Humans Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2021 Document type: Article Affiliation country: Estados Unidos Country of publication: Reino Unido