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Intradermal delivery of a synthetic DNA vaccine protects macaques from Middle East respiratory syndrome coronavirus.
Patel, Ami; Reuschel, Emma L; Xu, Ziyang; Zaidi, Faraz I; Kim, Kevin Y; Scott, Dana P; Mendoza, Janess; Ramos, Stephanie; Stoltz, Regina; Feldmann, Friederike; Okumura, Atsushi; Meade-White, Kimberly; Haddock, Elaine; Thomas, Tina; Rosenke, Rebecca; Lovaglio, Jamie; Hanley, Patrick W; Saturday, Greg; Muthumani, Kar; Feldmann, Heinz; Humeau, Laurent M; Broderick, Kate E; Weiner, David B.
Affiliation
  • Patel A; Vaccine & Immunotherapy Center, The Wistar Institute, Philadelphia, Pennsylvania, USA.
  • Reuschel EL; Vaccine & Immunotherapy Center, The Wistar Institute, Philadelphia, Pennsylvania, USA.
  • Xu Z; Vaccine & Immunotherapy Center, The Wistar Institute, Philadelphia, Pennsylvania, USA.
  • Zaidi FI; Department of Pharmacology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
  • Kim KY; Vaccine & Immunotherapy Center, The Wistar Institute, Philadelphia, Pennsylvania, USA.
  • Scott DP; Vaccine & Immunotherapy Center, The Wistar Institute, Philadelphia, Pennsylvania, USA.
  • Mendoza J; Rocky Mountain Veterinary Branch, Division of Intramural Research, National Institutes of Allergy and Infectious Diseases, NIH, Hamilton, Montana, USA.
  • Ramos S; Inovio Pharmaceuticals Inc., Plymouth Meeting, Pennsylvania, USA.
  • Stoltz R; Inovio Pharmaceuticals Inc., Plymouth Meeting, Pennsylvania, USA.
  • Feldmann F; Vaccine & Immunotherapy Center, The Wistar Institute, Philadelphia, Pennsylvania, USA.
  • Okumura A; Rocky Mountain Veterinary Branch, Division of Intramural Research, National Institutes of Allergy and Infectious Diseases, NIH, Hamilton, Montana, USA.
  • Meade-White K; Laboratory of Virology, Division of Intramural Research, National Institutes of Allergy and Infectious Diseases, NIH, Hamilton, Montana, USA.
  • Haddock E; Laboratory of Virology, Division of Intramural Research, National Institutes of Allergy and Infectious Diseases, NIH, Hamilton, Montana, USA.
  • Thomas T; Laboratory of Virology, Division of Intramural Research, National Institutes of Allergy and Infectious Diseases, NIH, Hamilton, Montana, USA.
  • Rosenke R; Rocky Mountain Veterinary Branch, Division of Intramural Research, National Institutes of Allergy and Infectious Diseases, NIH, Hamilton, Montana, USA.
  • Lovaglio J; Rocky Mountain Veterinary Branch, Division of Intramural Research, National Institutes of Allergy and Infectious Diseases, NIH, Hamilton, Montana, USA.
  • Hanley PW; Rocky Mountain Veterinary Branch, Division of Intramural Research, National Institutes of Allergy and Infectious Diseases, NIH, Hamilton, Montana, USA.
  • Saturday G; Rocky Mountain Veterinary Branch, Division of Intramural Research, National Institutes of Allergy and Infectious Diseases, NIH, Hamilton, Montana, USA.
  • Muthumani K; Rocky Mountain Veterinary Branch, Division of Intramural Research, National Institutes of Allergy and Infectious Diseases, NIH, Hamilton, Montana, USA.
  • Feldmann H; Vaccine & Immunotherapy Center, The Wistar Institute, Philadelphia, Pennsylvania, USA.
  • Humeau LM; Laboratory of Virology, Division of Intramural Research, National Institutes of Allergy and Infectious Diseases, NIH, Hamilton, Montana, USA.
  • Broderick KE; Inovio Pharmaceuticals Inc., Plymouth Meeting, Pennsylvania, USA.
  • Weiner DB; Inovio Pharmaceuticals Inc., Plymouth Meeting, Pennsylvania, USA.
JCI Insight ; 6(10)2021 05 24.
Article in En | MEDLINE | ID: mdl-33886507
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Viral Vaccines / Coronavirus Infections / Vaccines, DNA / Middle East Respiratory Syndrome Coronavirus / Macaca mulatta Limits: Animals Language: En Journal: JCI Insight Year: 2021 Document type: Article Affiliation country: Estados Unidos Country of publication: Estados Unidos
Fulltext
Add to My VHL
Print
XML
PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Viral Vaccines / Coronavirus Infections / Vaccines, DNA / Middle East Respiratory Syndrome Coronavirus / Macaca mulatta Limits: Animals Language: En Journal: JCI Insight Year: 2021 Document type: Article Affiliation country: Estados Unidos Country of publication: Estados Unidos