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Loss of enteric neuronal Ndrg4 promotes colorectal cancer via increased release of Nid1 and Fbln2.
Vaes, Nathalie; Schonkeren, Simone L; Rademakers, Glenn; Holland, Amy M; Koch, Alexander; Gijbels, Marion J; Keulers, Tom G; de Wit, Meike; Moonen, Laura; Van der Meer, Jaleesa R M; van den Boezem, Edith; Wolfs, Tim G A M; Threadgill, David W; Demmers, Jeroen; Fijneman, Remond J A; Jimenez, Connie R; Vanden Berghe, Pieter; Smits, Kim M; Rouschop, Kasper M A; Boesmans, Werend; Hofstra, Robert M W; Melotte, Veerle.
Affiliation
  • Vaes N; Department of Pathology, GROW-School for Oncology and Developmental Biology, Maastricht University Medical Center, Maastricht, The Netherlands.
  • Schonkeren SL; Department of Pathology, GROW-School for Oncology and Developmental Biology, Maastricht University Medical Center, Maastricht, The Netherlands.
  • Rademakers G; Department of Pathology, GROW-School for Oncology and Developmental Biology, Maastricht University Medical Center, Maastricht, The Netherlands.
  • Holland AM; Department of Pathology, GROW-School for Oncology and Developmental Biology, Maastricht University Medical Center, Maastricht, The Netherlands.
  • Koch A; Department of Pathology, GROW-School for Oncology and Developmental Biology, Maastricht University Medical Center, Maastricht, The Netherlands.
  • Gijbels MJ; Department of Pathology, GROW-School for Oncology and Developmental Biology, Maastricht University Medical Center, Maastricht, The Netherlands.
  • Keulers TG; Department of Molecular Genetics, Cardiovascular Research Institute Maastricht (CARIM), Maastricht, The Netherlands.
  • de Wit M; Department of Medical Biochemistry, Academic Medical Center, Amsterdam, The Netherlands.
  • Moonen L; Department of Radiotherapy, GROW-School for Oncology and Developmental Biology and Comprehensive Cancer Center Maastricht MUMC+, Maastricht University, Maastricht, The Netherlands.
  • Van der Meer JRM; Department of Medical Oncology and Oncoproteomics Laboratory, Cancer Center Amsterdam, Vrije Universiteit Amsterdam, Amsterdam UMC, Amsterdam, The Netherlands.
  • van den Boezem E; Department of Pathology, Netherlands Cancer Institute, Amsterdam, The Netherlands.
  • Wolfs TGAM; Department of Pathology, GROW-School for Oncology and Developmental Biology, Maastricht University Medical Center, Maastricht, The Netherlands.
  • Threadgill DW; Department of Pathology, GROW-School for Oncology and Developmental Biology, Maastricht University Medical Center, Maastricht, The Netherlands.
  • Demmers J; Department of Pathology, GROW-School for Oncology and Developmental Biology, Maastricht University Medical Center, Maastricht, The Netherlands.
  • Fijneman RJA; Department of Pediatrics, GROW-School for Oncology and Developmental Biology, Maastricht University, Maastricht, The Netherlands.
  • Jimenez CR; Department of Molecular and Cellular Medicine, Texas A&M University Health Science Center, College Station, TX, USA.
  • Vanden Berghe P; Department of Biochemistry and Biophysics, Texas A&M University, College Station, TX, USA.
  • Smits KM; Proteomics Center, Erasmus University Medical Center, Rotterdam, The Netherlands.
  • Rouschop KMA; Department of Pathology, Netherlands Cancer Institute, Amsterdam, The Netherlands.
  • Boesmans W; Department of Medical Oncology and Oncoproteomics Laboratory, Cancer Center Amsterdam, Vrije Universiteit Amsterdam, Amsterdam UMC, Amsterdam, The Netherlands.
  • Hofstra RMW; Laboratory for Enteric Neuroscience (LENS) and Translational Research Center for Gastrointestinal Disorders (TARGID), Department of Chronic Diseases, Metabolism and Ageing, KU Leuven, Leuven, Belgium.
  • Melotte V; Department of Pathology, GROW-School for Oncology and Developmental Biology, Maastricht University Medical Center, Maastricht, The Netherlands.
EMBO Rep ; 22(6): e51913, 2021 06 04.
Article in En | MEDLINE | ID: mdl-33890711

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Colorectal Neoplasms / Enteric Nervous System Limits: Humans Language: En Journal: EMBO Rep Journal subject: BIOLOGIA MOLECULAR Year: 2021 Document type: Article Affiliation country: Países Bajos Country of publication: Reino Unido

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Colorectal Neoplasms / Enteric Nervous System Limits: Humans Language: En Journal: EMBO Rep Journal subject: BIOLOGIA MOLECULAR Year: 2021 Document type: Article Affiliation country: Países Bajos Country of publication: Reino Unido