Uncertainty propagation and sensitivity analysis: results from the Ocular Mathematical Virtual Simulator.
Math Biosci Eng
; 18(3): 2010-2032, 2021 03 02.
Article
in En
| MEDLINE
| ID: mdl-33892535
ABSTRACT
We propose an uncertainty propagation study and a sensitivity analysis with the Ocular Mathematical Virtual Simulator, a computational and mathematical model that predicts the hemodynamics and biomechanics within the human eye. In this contribution, we focus on the effect of intraocular pressure, retrolaminar tissue pressure and systemic blood pressure on the ocular posterior tissue vasculature. The combination of a physically-based model with experiments-based stochastic input allows us to gain a better understanding of the physiological system, accounting both for the driving mechanisms and the data variability.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Hemodynamics
/
Intraocular Pressure
Type of study:
Diagnostic_studies
/
Prognostic_studies
Limits:
Humans
Language:
En
Journal:
Math Biosci Eng
Year:
2021
Document type:
Article
Affiliation country:
Francia