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Introduction, Transmission Dynamics, and Fate of Early Severe Acute Respiratory Syndrome Coronavirus 2 Lineages in Santa Clara County, California.
Villarino, Elsa; Deng, Xianding; Kemper, Carol A; Jorden, Michelle A; Bonin, Brandon; Rudman, Sarah L; Han, George S; Yu, Guixia; Wang, Candace; Federman, Scot; Bushnell, Brian; Wadford, Debra A; Lin, Wen; Tao, Ying; Paden, Clinton R; Bhatnagar, Julu; MacCannell, Tara; Tong, Suxiang; Batson, Joshua; Chiu, Charles Y.
Affiliation
  • Villarino E; County of Santa Clara Public Health Department, San Jose, California, USA.
  • Deng X; Department of Laboratory Medicine, University of California, San Francisco, San Francisco, California, USA.
  • Kemper CA; UCSF-Abbott Viral Diagnostics and Discovery Center, San Francisco, California, USA.
  • Jorden MA; El Camino Hospital, Mountain View and Los Gatos, California, USA.
  • Bonin B; Office of the Medical Examiner-Coroner, County of Santa Clara, San Jose, California, USA.
  • Rudman SL; County of Santa Clara Public Health Department, San Jose, California, USA.
  • Han GS; County of Santa Clara Public Health Department, San Jose, California, USA.
  • Yu G; County of Santa Clara Public Health Department, San Jose, California, USA.
  • Wang C; Department of Laboratory Medicine, University of California, San Francisco, San Francisco, California, USA.
  • Federman S; UCSF-Abbott Viral Diagnostics and Discovery Center, San Francisco, California, USA.
  • Bushnell B; Department of Laboratory Medicine, University of California, San Francisco, San Francisco, California, USA.
  • Wadford DA; Department of Laboratory Medicine, University of California, San Francisco, San Francisco, California, USA.
  • Lin W; UCSF-Abbott Viral Diagnostics and Discovery Center, San Francisco, California, USA.
  • Tao Y; Lawrence Berkeley National Laboratory, Berkeley, California, USA.
  • Bhatnagar J; Viral and Rickettsial Disease Laboratory, California Department of Public Health, Richmond, California, USA.
  • MacCannell T; County of Santa Clara Public Health Department, San Jose, California, USA.
  • Tong S; Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
  • Batson J; Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
  • Chiu CY; Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
J Infect Dis ; 224(2): 207-217, 2021 07 15.
Article in En | MEDLINE | ID: mdl-33893501
ABSTRACT
We combined viral genome sequencing with contact tracing to investigate introduction and evolution of severe acute respiratory syndrome coronavirus 2 lineages in Santa Clara County, California, from 27 January to 21 March 2020. From 558 persons with coronavirus disease 2019, 101 genomes from 143 available clinical samples comprised 17 lineages, including SCC1 (n = 41), WA1 (n = 9; including the first 2 reported deaths in the United States, with postmortem diagnosis), D614G (n = 4), ancestral Wuhan Hu-1 (n = 21), and 13 others (n = 26). Public health intervention may have curtailed the persistence of lineages that appeared transiently during February and March. By August, only D614G lineages introduced after 21 March were circulating in Santa Clara County.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: SARS-CoV-2 / COVID-19 Type of study: Etiology_studies / Risk_factors_studies Limits: Adult / Aged / Female / Humans / Male / Middle aged Country/Region as subject: America do norte Language: En Journal: J Infect Dis Year: 2021 Document type: Article Affiliation country: Estados Unidos
Fulltext
Add to My VHL
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: SARS-CoV-2 / COVID-19 Type of study: Etiology_studies / Risk_factors_studies Limits: Adult / Aged / Female / Humans / Male / Middle aged Country/Region as subject: America do norte Language: En Journal: J Infect Dis Year: 2021 Document type: Article Affiliation country: Estados Unidos