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Bavachin enhances NLRP3 inflammasome activation induced by ATP or nigericin and causes idiosyncratic hepatotoxicity.
Qin, Nan; Xu, Guang; Wang, Yan; Zhan, Xiaoyan; Gao, Yuan; Wang, Zhilei; Fu, Shubin; Shi, Wei; Hou, Xiaorong; Wang, Chunyu; Li, Ruisheng; Liu, Yan; Wang, Jiabo; Zhao, Haiping; Xiao, Xiaohe; Bai, Zhaofang.
Affiliation
  • Qin N; China Military Institute of Chinese Materia, the Fifth Medical Centre, Chinese PLA General Hospital, Beijing, 100039, China.
  • Xu G; Department of Pharmacy, Nantong Hospital of Traditional Chinese Medicine, Nantong, 226300, China.
  • Wang Y; China Military Institute of Chinese Materia, the Fifth Medical Centre, Chinese PLA General Hospital, Beijing, 100039, China.
  • Zhan X; China Military Institute of Chinese Materia, the Fifth Medical Centre, Chinese PLA General Hospital, Beijing, 100039, China.
  • Gao Y; School of Pharmacy, Henan University of Chinese Medicine, Zhengzhou, 450046, China.
  • Wang Z; China Military Institute of Chinese Materia, the Fifth Medical Centre, Chinese PLA General Hospital, Beijing, 100039, China.
  • Fu S; School of Traditional Chinese Medicine, Capital Medical University, Beijing, 100069, China.
  • Shi W; China Military Institute of Chinese Materia, the Fifth Medical Centre, Chinese PLA General Hospital, Beijing, 100039, China.
  • Hou X; China Military Institute of Chinese Materia, the Fifth Medical Centre, Chinese PLA General Hospital, Beijing, 100039, China.
  • Wang C; China Military Institute of Chinese Materia, the Fifth Medical Centre, Chinese PLA General Hospital, Beijing, 100039, China.
  • Li R; China Military Institute of Chinese Materia, the Fifth Medical Centre, Chinese PLA General Hospital, Beijing, 100039, China.
  • Liu Y; China Military Institute of Chinese Materia, the Fifth Medical Centre, Chinese PLA General Hospital, Beijing, 100039, China.
  • Wang J; Research Center for Clinical and Translational Medicine, the Fifth Medical Centre, Chinese PLA General Hospital, Beijing, 100039, China.
  • Zhao H; Research Center for Clinical and Translational Medicine, the Fifth Medical Centre, Chinese PLA General Hospital, Beijing, 100039, China.
  • Xiao X; China Military Institute of Chinese Materia, the Fifth Medical Centre, Chinese PLA General Hospital, Beijing, 100039, China.
  • Bai Z; School of Traditional Chinese Medicine, Jiangxi University of Traditional Chinese Medicine, Nanchang, 330004, China. cdzhp3690098@163.com.
Front Med ; 15(4): 594-607, 2021 Aug.
Article in En | MEDLINE | ID: mdl-33909257
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Chemical and Drug Induced Liver Injury / Inflammasomes Type of study: Etiology_studies / Prognostic_studies Limits: Animals / Humans Language: En Journal: Front Med Year: 2021 Document type: Article Affiliation country: China
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Chemical and Drug Induced Liver Injury / Inflammasomes Type of study: Etiology_studies / Prognostic_studies Limits: Animals / Humans Language: En Journal: Front Med Year: 2021 Document type: Article Affiliation country: China