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Design, synthesis and biological evaluation of a series of iron and copper chelating deferiprone derivatives as new agents active against Candida albicans.
Bortolami, Martina; Pandolfi, Fabiana; Messore, Antonella; Rocco, Daniele; Feroci, Marta; Di Santo, Roberto; De Vita, Daniela; Costi, Roberta; Cascarino, Paola; Simonetti, Giovanna; Scipione, Luigi.
Affiliation
  • Bortolami M; Department of Scienze di Base e Applicate per l'Ingegneria, Sapienza University of Rome, via Castro Laurenziano 7, 00161 Rome, Italy.
  • Pandolfi F; Department of Scienze di Base e Applicate per l'Ingegneria, Sapienza University of Rome, via Castro Laurenziano 7, 00161 Rome, Italy. Electronic address: fabiana.pandolfi@uniroma1.it.
  • Messore A; Department of Chimica e Tecnologia del Farmaco, Sapienza University of Rome, Piazzale Aldo Moro 5, 00185 Rome, Italy.
  • Rocco D; Department of Scienze di Base e Applicate per l'Ingegneria, Sapienza University of Rome, via Castro Laurenziano 7, 00161 Rome, Italy.
  • Feroci M; Department of Scienze di Base e Applicate per l'Ingegneria, Sapienza University of Rome, via Castro Laurenziano 7, 00161 Rome, Italy.
  • Di Santo R; Department of Chimica e Tecnologia del Farmaco, Sapienza University of Rome, Piazzale Aldo Moro 5, 00185 Rome, Italy; Istituto Pasteur, Fondazione Cenci Bolognetti, Department of Chemistry and Technology of Drug, Sapienza University of Rome, Piazzale Aldo Moro 5, 00185 Rome, Italy.
  • De Vita D; Department of Environmental Biology, Sapienza University of Rome, Piazzale Aldo Moro 5, 00185 Rome, Italy.
  • Costi R; Department of Chimica e Tecnologia del Farmaco, Sapienza University of Rome, Piazzale Aldo Moro 5, 00185 Rome, Italy; Istituto Pasteur, Fondazione Cenci Bolognetti, Department of Chemistry and Technology of Drug, Sapienza University of Rome, Piazzale Aldo Moro 5, 00185 Rome, Italy.
  • Cascarino P; Department of Public Health and Infectious Diseases, Sapienza University of Rome, Piazzale Aldo Moro 5, 00185 Rome, Italy.
  • Simonetti G; Department of Environmental Biology, Sapienza University of Rome, Piazzale Aldo Moro 5, 00185 Rome, Italy. Electronic address: giovanna.simonetti@uniroma1.it.
  • Scipione L; Department of Chimica e Tecnologia del Farmaco, Sapienza University of Rome, Piazzale Aldo Moro 5, 00185 Rome, Italy.
Bioorg Med Chem Lett ; 42: 128087, 2021 06 15.
Article in En | MEDLINE | ID: mdl-33964446
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Candida albicans / Chelating Agents / Copper / Deferiprone / Iron / Antifungal Agents Language: En Journal: Bioorg Med Chem Lett Journal subject: BIOQUIMICA / QUIMICA Year: 2021 Document type: Article Affiliation country: Italia
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Candida albicans / Chelating Agents / Copper / Deferiprone / Iron / Antifungal Agents Language: En Journal: Bioorg Med Chem Lett Journal subject: BIOQUIMICA / QUIMICA Year: 2021 Document type: Article Affiliation country: Italia