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R (-)-methoxetamine exerts rapid and sustained antidepressant effects and fewer behavioral side effects relative to S (+)-methoxetamine.
Botanas, Chrislean Jun; Perez Custodio, Raly James; Kim, Hee Jin; de la Pena, June Bryan; Sayson, Leandro Val; Ortiz, Darlene Mae; Kim, Mikyung; Lee, Hyun Jun; Acharya, Srijan; Kim, Kyeong-Man; Lee, Cheol Jung; Ryu, Jong Hoon; Lee, Yong Sup; Cheong, Jae Hoon.
Affiliation
  • Botanas CJ; Uimyung Research Institute for Neuroscience, College of Pharmacy, Sahmyook University, 815 Hwarang-ro, Nowon-gu, Seoul, 01795, Republic of Korea.
  • Perez Custodio RJ; Uimyung Research Institute for Neuroscience, College of Pharmacy, Sahmyook University, 815 Hwarang-ro, Nowon-gu, Seoul, 01795, Republic of Korea.
  • Kim HJ; Uimyung Research Institute for Neuroscience, College of Pharmacy, Sahmyook University, 815 Hwarang-ro, Nowon-gu, Seoul, 01795, Republic of Korea.
  • de la Pena JB; Uimyung Research Institute for Neuroscience, College of Pharmacy, Sahmyook University, 815 Hwarang-ro, Nowon-gu, Seoul, 01795, Republic of Korea; Department of Biological Sciences, University of Texas Dallas, Richardson, TX, 75080, United States.
  • Sayson LV; Uimyung Research Institute for Neuroscience, College of Pharmacy, Sahmyook University, 815 Hwarang-ro, Nowon-gu, Seoul, 01795, Republic of Korea.
  • Ortiz DM; Uimyung Research Institute for Neuroscience, College of Pharmacy, Sahmyook University, 815 Hwarang-ro, Nowon-gu, Seoul, 01795, Republic of Korea.
  • Kim M; Uimyung Research Institute for Neuroscience, College of Pharmacy, Sahmyook University, 815 Hwarang-ro, Nowon-gu, Seoul, 01795, Republic of Korea; Department of Chemistry and Life Science, Sahmyook University, 815 Hwarang-ro, Nowon-gu, Seoul, 01795, Republic of Korea.
  • Lee HJ; Uimyung Research Institute for Neuroscience, College of Pharmacy, Sahmyook University, 815 Hwarang-ro, Nowon-gu, Seoul, 01795, Republic of Korea.
  • Acharya S; Department of Pharmacology, College of Pharmacy, Chonnam National University, Gwangju, 61186, Republic of Korea.
  • Kim KM; Department of Pharmacology, College of Pharmacy, Chonnam National University, Gwangju, 61186, Republic of Korea.
  • Lee CJ; Medicinal Chemistry Laboratory, Department of Pharmacy & Department of Life and Nanopharmaceutical Sciences, College of Pharmacy, Kyung Hee University, 26 Kyungheedae-ro, Seoul, 02447, Republic of Korea.
  • Ryu JH; Department of Life and Nanopharmaceutical Science, Department of Oriental Pharmaceutical Science, College of Pharmacy, Kyung Hee University, 26 Kyungheedae-ro, Seoul, 02447, Republic of Korea.
  • Lee YS; Medicinal Chemistry Laboratory, Department of Pharmacy & Department of Life and Nanopharmaceutical Sciences, College of Pharmacy, Kyung Hee University, 26 Kyungheedae-ro, Seoul, 02447, Republic of Korea. Electronic address: kyslee@khu.ac.kr.
  • Cheong JH; School of Pharmacy, Jeonbuk National University, 567 Baekje-daero, Deokjin-gu, Jeonju-si, Jeollabuk-do, 54896 Republic of Korea. Electronic address: cheongjh@jbnu.ac.kr.
Neuropharmacology ; 193: 108619, 2021 08 01.
Article in En | MEDLINE | ID: mdl-34023336
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cyclohexanones / Cyclohexylamines / Depression / Antidepressive Agents Type of study: Prognostic_studies Limits: Animals / Humans / Male Language: En Journal: Neuropharmacology Year: 2021 Document type: Article Country of publication: Reino Unido
Fulltext
Add to My VHL
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cyclohexanones / Cyclohexylamines / Depression / Antidepressive Agents Type of study: Prognostic_studies Limits: Animals / Humans / Male Language: En Journal: Neuropharmacology Year: 2021 Document type: Article Country of publication: Reino Unido