Multi-omics approaches identify SF3B3 and SIRT3 as candidate autophagic regulators and druggable targets in invasive breast carcinoma.
Acta Pharm Sin B
; 11(5): 1227-1245, 2021 May.
Article
in En
| MEDLINE
| ID: mdl-34094830
ATG, autophagy-related gene; Anti-proliferation; Autophagic regulator; BRCA, invasive breast carcinoma; CNA, copy number alteration; Druggable target; EXP, gene expression; GO, Gene Ontology; Invasive breast carcinoma; LASSO, least absolute shrinkage and selection operator; MET, DNA methylation; Migration; Multi-omics approach; PFS, progression-free survival; SF3B3; SIRT3; SNF, similarity network fusion; TCGA, The Cancer Genome Atlas; TNBC, triple-negative breast cancer
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Language:
En
Journal:
Acta Pharm Sin B
Year:
2021
Document type:
Article
Affiliation country:
China
Country of publication:
Países Bajos