ß-sitosterol reduces anxiety and synergizes with established anxiolytic drugs in mice.

Panayotis, Nicolas; Freund, Philip A; Marvaldi, Letizia; Shalit, Tali; Brandis, Alexander; Mehlman, Tevie; Tsoory, Michael M; Fainzilber, Mike

Panayotis, Nicolas; Freund, Philip A; Marvaldi, Letizia; Shalit, Tali; Brandis, Alexander; Mehlman, Tevie; Tsoory, Michael M; Fainzilber, Mike.

Affiliation

Panayotis N; Department of Biomolecular Sciences, Weizmann Institute of Science, Rehovot, Israel.
Freund PA; Department of Biomolecular Sciences, Weizmann Institute of Science, Rehovot, Israel.
Marvaldi L; Department of Biomolecular Sciences, Weizmann Institute of Science, Rehovot, Israel.
Shalit T; Ilana and Pascal Mantoux Institute for Bioinformatics, The Nancy and Stephen Grand Israel National Center for Personalized Medicine, Weizmann Institute of Science, Rehovot, Israel.
Brandis A; Life Science Core Facility, Weizmann Institute of Science, Rehovot, Israel.
Mehlman T; Life Science Core Facility, Weizmann Institute of Science, Rehovot, Israel.
Tsoory MM; Department of Veterinary Resources, Weizmann Institute of Science, Rehovot, Israel.
Fainzilber M; Department of Biomolecular Sciences, Weizmann Institute of Science, Rehovot, Israel.

Cell Rep Med ; 2(5): 100281, 2021 05 18.

Article in En | MEDLINE | ID: mdl-34095883

Subject(s)
Key words

CNS drugs; SSRIs; anxiolytics; drug repositioning; fluoxetine; metabolomics; phytosterol; transcriptomics; ß-Sitosterol

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Anxiety / Anxiety Disorders / Sitosterols / Anti-Anxiety Agents Type of study: Prognostic_studies Limits: Animals Language: En Journal: Cell Rep Med Year: 2021 Document type: Article Affiliation country: Israel Country of publication: Estados Unidos

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