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Nanoparticle Delivery of STAT3 Alleviates Pulmonary Hypertension in a Mouse Model of Alveolar Capillary Dysplasia.
Sun, Fei; Wang, Guolun; Pradhan, Arun; Xu, Kui; Gomez-Arroyo, Jose; Zhang, Yufang; Kalin, Gregory T; Deng, Zicheng; Vagnozzi, Ronald J; He, Hua; Dunn, Andrew W; Wang, Yuhua; York, Allen J; Hegde, Rashmi S; Woods, Jason C; Kalin, Tanya V; Molkentin, Jeffery D; Kalinichenko, Vladimir V.
Affiliation
  • Sun F; Center for Lung Regenerative Medicine, Perinatal Institute (F.S., G.W., A.P., K.X., J.G.-A., Y.Z., G.T.K., Z.D., A.W.D., V.V.K.), Cincinnati Children's Hospital Medical Center, OH.
  • Wang G; Center for Lung Regenerative Medicine, Perinatal Institute (F.S., G.W., A.P., K.X., J.G.-A., Y.Z., G.T.K., Z.D., A.W.D., V.V.K.), Cincinnati Children's Hospital Medical Center, OH.
  • Pradhan A; Center for Lung Regenerative Medicine, Perinatal Institute (F.S., G.W., A.P., K.X., J.G.-A., Y.Z., G.T.K., Z.D., A.W.D., V.V.K.), Cincinnati Children's Hospital Medical Center, OH.
  • Xu K; Center for Lung Regenerative Medicine, Perinatal Institute (F.S., G.W., A.P., K.X., J.G.-A., Y.Z., G.T.K., Z.D., A.W.D., V.V.K.), Cincinnati Children's Hospital Medical Center, OH.
  • Gomez-Arroyo J; Center for Lung Regenerative Medicine, Perinatal Institute (F.S., G.W., A.P., K.X., J.G.-A., Y.Z., G.T.K., Z.D., A.W.D., V.V.K.), Cincinnati Children's Hospital Medical Center, OH.
  • Zhang Y; Department of Internal Medicine, Section of Pulmonary and Critical Care (J.G.-A.), University of Cincinnati, OH.
  • Kalin GT; Center for Lung Regenerative Medicine, Perinatal Institute (F.S., G.W., A.P., K.X., J.G.-A., Y.Z., G.T.K., Z.D., A.W.D., V.V.K.), Cincinnati Children's Hospital Medical Center, OH.
  • Deng Z; Center for Lung Regenerative Medicine, Perinatal Institute (F.S., G.W., A.P., K.X., J.G.-A., Y.Z., G.T.K., Z.D., A.W.D., V.V.K.), Cincinnati Children's Hospital Medical Center, OH.
  • Vagnozzi RJ; Division of Pulmonary Biology (G.T.K., H.H., T.V.K., J.D.M., V.V.K.), Cincinnati Children's Hospital Medical Center, OH.
  • He H; Center for Lung Regenerative Medicine, Perinatal Institute (F.S., G.W., A.P., K.X., J.G.-A., Y.Z., G.T.K., Z.D., A.W.D., V.V.K.), Cincinnati Children's Hospital Medical Center, OH.
  • Dunn AW; The Materials Science and Engineering Program, College of Engineering and Applied Science (Z.D., A.W.D.), University of Cincinnati, OH.
  • Wang Y; Division of Molecular Cardiovascular Biology, Heart Institute (R.J.V., A.J.Y., J.D.M.), Cincinnati Children's Hospital Medical Center, OH.
  • York AJ; Division of Pulmonary Biology (G.T.K., H.H., T.V.K., J.D.M., V.V.K.), Cincinnati Children's Hospital Medical Center, OH.
  • Hegde RS; Center for Lung Regenerative Medicine, Perinatal Institute (F.S., G.W., A.P., K.X., J.G.-A., Y.Z., G.T.K., Z.D., A.W.D., V.V.K.), Cincinnati Children's Hospital Medical Center, OH.
  • Woods JC; The Materials Science and Engineering Program, College of Engineering and Applied Science (Z.D., A.W.D.), University of Cincinnati, OH.
  • Kalin TV; Division of Developmental Biology (Y.W., R.S.H., V.V.K.), Cincinnati Children's Hospital Medical Center, OH.
  • Molkentin JD; Division of Molecular Cardiovascular Biology, Heart Institute (R.J.V., A.J.Y., J.D.M.), Cincinnati Children's Hospital Medical Center, OH.
  • Kalinichenko VV; Division of Developmental Biology (Y.W., R.S.H., V.V.K.), Cincinnati Children's Hospital Medical Center, OH.
Circulation ; 144(7): 539-555, 2021 08 17.
Article in En | MEDLINE | ID: mdl-34111939
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Persistent Fetal Circulation Syndrome / Pulmonary Alveoli / Gene Transfer Techniques / STAT3 Transcription Factor / Nanoparticles / Hypertension, Pulmonary Type of study: Diagnostic_studies / Etiology_studies / Prognostic_studies Limits: Animals / Humans Language: En Journal: Circulation Year: 2021 Document type: Article
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Persistent Fetal Circulation Syndrome / Pulmonary Alveoli / Gene Transfer Techniques / STAT3 Transcription Factor / Nanoparticles / Hypertension, Pulmonary Type of study: Diagnostic_studies / Etiology_studies / Prognostic_studies Limits: Animals / Humans Language: En Journal: Circulation Year: 2021 Document type: Article