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The GLP-1/GIP dual-receptor agonist DA5-CH inhibits the NF-κB inflammatory pathway in the MPTP mouse model of Parkinson's disease more effectively than the GLP-1 single-receptor agonist NLY01.
Lv, MiaoJun; Xue, GuoFang; Cheng, HuiFeng; Meng, PengFei; Lian, Xia; Hölscher, Christian; Li, DongFang.
Affiliation
  • Lv M; Second Hospital, Neurology Department, Shanxi Medical University, Taiyuan, Shanxi Province, People's Republic of China.
  • Xue G; Second Hospital, Neurology Department, Shanxi Medical University, Taiyuan, Shanxi Province, People's Republic of China.
  • Cheng H; Second Hospital, Neurology Department, Shanxi Medical University, Taiyuan, Shanxi Province, People's Republic of China.
  • Meng P; Second Hospital, Neurology Department, Shanxi Medical University, Taiyuan, Shanxi Province, People's Republic of China.
  • Lian X; Second Hospital, Neurology Department, Shanxi Medical University, Taiyuan, Shanxi Province, People's Republic of China.
  • Hölscher C; Second Hospital, Neurology Department, Shanxi Medical University, Taiyuan, Shanxi Province, People's Republic of China.
  • Li D; Research and Experimental Center, Henan University of Chinese Medicine, Zhengzhou, Henan Province, People's Republic of China.
Brain Behav ; 11(8): e2231, 2021 08.
Article in En | MEDLINE | ID: mdl-34125470
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Parkinson Disease / Pharmaceutical Preparations / Neuroprotective Agents Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Brain Behav Year: 2021 Document type: Article Country of publication: Estados Unidos
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Parkinson Disease / Pharmaceutical Preparations / Neuroprotective Agents Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Brain Behav Year: 2021 Document type: Article Country of publication: Estados Unidos