Proteasome dysfunction under compromised redox metabolism dictates liver injury in NASH through ASK1/PPARÎ³ binodal complementary modules.

Das, Debajyoti; Paul, Avishek; Lahiri, Abhishake; Adak, Moumita; Maity, Sujay K; Sarkar, Ankita; Paul, Sandip; Chakrabarti, Partha

Das, Debajyoti; Paul, Avishek; Lahiri, Abhishake; Adak, Moumita; Maity, Sujay K; Sarkar, Ankita; Paul, Sandip; Chakrabarti, Partha.

Affiliation

Das D; Division of Cell Biology and Physiology, CSIR-Indian Institute of Chemical Biology, Kolkata, India.
Paul A; Division of Cell Biology and Physiology, CSIR-Indian Institute of Chemical Biology, Kolkata, India.
Lahiri A; Division of Structural Biology & Bioinformatics, CSIR-Indian Institute of Chemical Biology, Kolkata, India.
Adak M; Division of Cell Biology and Physiology, CSIR-Indian Institute of Chemical Biology, Kolkata, India.
Maity SK; Division of Cell Biology and Physiology, CSIR-Indian Institute of Chemical Biology, Kolkata, India.
Sarkar A; Division of Cell Biology and Physiology, CSIR-Indian Institute of Chemical Biology, Kolkata, India.
Paul S; Division of Structural Biology & Bioinformatics, CSIR-Indian Institute of Chemical Biology, Kolkata, India; JIS Institute of Advanced Studies and Research, JIS University, Kolkata, India.
Chakrabarti P; Division of Cell Biology and Physiology, CSIR-Indian Institute of Chemical Biology, Kolkata, India. Electronic address: pchakrabarti@iicb.res.in.

Redox Biol ; 45: 102043, 2021 09.

Article in En | MEDLINE | ID: mdl-34144391

Subject(s)
Key words

ASK1; Liver; NASH; PPARÎ³; Proteasome

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Non-alcoholic Fatty Liver Disease Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Redox Biol Year: 2021 Document type: Article Affiliation country: India

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