Off-hours admission does not impact outcomes in patients undergoing primary percutaneous coronary intervention and with a first medical contact-to-device time within 90âmin.
Chin Med J (Engl)
; 134(15): 1795-1802, 2021 Jun 24.
Article
in En
| MEDLINE
| ID: mdl-34172617
ABSTRACT
BACKGROUND:
It remains unclear whether the outcomes of ST-elevation myocardial infarction (STEMI) patients treated with primary percutaneous coronary intervention (PPCI) during off-hours are as favorable as those treated during on-hours, especially those with a first medical contact-to-device (FMC-to-device) time within 90âmin. We aimed to determine whether off-hours admission impacted late outcomes in patients undergoing PPCI and with an FMC-to-device time ≤90âmin.METHODS:
This multicenter retrospective study included 670 STEMI patients who underwent successful PPCI and had an FMC-to-device time ≤90âmin from 19 chest pain centers in Beijing from January 2018 to December 2018. Patients were divided into on-hours group and off-hours group based on their arrival time. Baseline characteristics, clinical data, and key time intervals during treatment were collected from the Quality Control & Improvement Center of Cardiovascular Intervention of Beijing by the "Heart and Brain Green Channel" app.RESULTS:
Overall, the median age of the patients was 58.8âyears and 19.9% (133/670) were female. Of these, 296 (44.2%) patients underwent PPCI during on-hours and 374 (55.8%) patients underwent PPCI during off-hours. Compared with the on-hours group, the off-hours group had a longer FMC-to-device time and fewer patients with FMC-to-device time ≤60âmin (Pâ<â0.05). During the mean follow-up period of 24âmonths, a total of 64 (9.6%) participants experienced a major adverse cardiovascular event (MACE), with 28 (9.1%) in the on-hours group and 36 (9.6%) in the off-hours group (Pâ>â0.05). According to the Cox regression analyses, off-hours admission was not a predictor of 2-year MACEs (Pâ=â0.788). Similarly, the Kaplan-Meier curves showed that the risks of a MACE, all-cause death, reinfarction, and target vessel revascularization were not significantly different between the two groups (Pâ>â0.05).CONCLUSIONS:
This real-world, multicenter retrospective study demonstrated that for STEMI patients who underwent PPCI within 90âmin, off-hours admission was safe, with no difference in the risk of 2-year MACEs compared with those with on-hours admission.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Percutaneous Coronary Intervention
/
ST Elevation Myocardial Infarction
Type of study:
Etiology_studies
/
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Limits:
Female
/
Humans
/
Middle aged
Country/Region as subject:
Asia
Language:
En
Journal:
Chin Med J (Engl)
Year:
2021
Document type:
Article
Affiliation country:
China