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Joint and entheseal inflammation in the knee region in spondyloarthritis - reliability and responsiveness of two OMERACT whole-body MRI scores.
Wetterslev, Marie; Maksymowych, Walter P; Lambert, Robert Gw; Eshed, Iris; Pedersen, Susanne J; Stoenoiu, Maria S; Krabbe, Simon; Bird, Paul; Foltz, Violaine; Mathew, Ashish J; Gandjbakhch, Frédérique; Paschke, Joel; Carron, Philippe; De Marco, Gabriele; Marzo-Ortega, Helena; Poulsen, Anna Ef; Jaremko, Jacob L; Conaghan, Philip G; Østergaard, Mikkel.
Affiliation
  • Wetterslev M; Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Copenhagen, Denmark; Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark. Electronic address: marie.wetterslev@regionh.dk.
  • Maksymowych WP; Department of Medicine, University of Alberta, Edmonton, Alberta, Canada; CARE Arthritis, Edmonton, Alberta, Canada.
  • Lambert RG; Department of Radiology and Diagnostic Imaging, University of Alberta, Edmonton, Alberta, Canada; Medical Imaging Consultants, Edmonton, Alberta, Canada.
  • Eshed I; Department of Diagnostic Imaging, Sheba Medical Center, Affiliated to the Sackler School of Medicine, Tel-Aviv University, Israel.
  • Pedersen SJ; Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Copenhagen, Denmark.
  • Stoenoiu MS; Department of Rheumatology, Cliniques Universitaires Saint-Luc, Institut de Recherche Expérimentale et Clinique, Université catholique de Louvain, Bruxelles, Belgium.
  • Krabbe S; Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Copenhagen, Denmark.
  • Bird P; Division of Medicine, University of New South Wales, Sydney, Australia.
  • Foltz V; Department of Rheumatology, Sorbonne University, APHP, Pitié-Salpêtrière Hospital, Paris, France.
  • Mathew AJ; Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Copenhagen, Denmark; Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark.
  • Gandjbakhch F; Department of Rheumatology, Sorbonne University, APHP, Pitié-Salpêtrière Hospital, Paris, France.
  • Paschke J; CARE Arthritis, Edmonton, Alberta, Canada.
  • Carron P; Department of Rheumatology, Ghent University Hospital, Ghent, Belgium; VIB Inflammation Research Centre, Ghent University, Ghent, Belgium.
  • De Marco G; Leeds Institute of Rheumatic and Musculoskeletal medicine, University of Leeds, Leeds, UK; Leeds Teaching Hospitals NHS Trust, NIHR Leeds Biomedical Research Centre, Leeds, UK.
  • Marzo-Ortega H; Leeds Institute of Rheumatic and Musculoskeletal medicine, University of Leeds, Leeds, UK; Leeds Teaching Hospitals NHS Trust, NIHR Leeds Biomedical Research Centre, Leeds, UK.
  • Poulsen AE; Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Copenhagen, Denmark.
  • Jaremko JL; Department of Radiology and Diagnostic Imaging, University of Alberta, Edmonton, Alberta, Canada.
  • Conaghan PG; Leeds Institute of Rheumatic and Musculoskeletal medicine, University of Leeds, Leeds, UK; Leeds Teaching Hospitals NHS Trust, NIHR Leeds Biomedical Research Centre, Leeds, UK.
  • Østergaard M; Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Copenhagen, Denmark; Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark.
Semin Arthritis Rheum ; 51(4): 933-939, 2021 08.
Article in En | MEDLINE | ID: mdl-34176643
ABSTRACT

OBJECTIVE:

To perform region-based development of whole-body MRI through validation of knee region scoring systems in spondyloarthritis (SpA).

METHODS:

Assessment of knee inflammatory pathologies using 2 systems, OMERACT MRI Whole-body score for Inflammation in Peripheral joints and Entheses (MRI-WIPE) and Knee Inflammation MRI Scoring System (KIMRISS), in 4 iterative multi-reader exercises.

RESULTS:

In the final exercise, reliability was mostly good for readers with highest agreement in previous exercise. Median pairwise single-measure ICCs for osteitis and synovitis/effusion status/change were 0.71/0.48 (WIPE-osteitis), 0.48/0.77 (WIPE-synovitis/effusion), 0.59/0.91 (KIMRISS-osteitis) and 0.92/0.97 (KIMRISS-synovitis/effusion). SRMs were 0.74 (WIPE-synovitis/effusion) and 0.78 (KIMRISS-synovitis/effusion).

CONCLUSION:

MRI-WIPE and KIMRISS may both be useful in SpA whole-body evaluation studies.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Synovitis / Spondylarthritis Limits: Humans Language: En Journal: Semin Arthritis Rheum Year: 2021 Document type: Article Country of publication: EEUU / ESTADOS UNIDOS / ESTADOS UNIDOS DA AMERICA / EUA / UNITED STATES / UNITED STATES OF AMERICA / US / USA

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Synovitis / Spondylarthritis Limits: Humans Language: En Journal: Semin Arthritis Rheum Year: 2021 Document type: Article Country of publication: EEUU / ESTADOS UNIDOS / ESTADOS UNIDOS DA AMERICA / EUA / UNITED STATES / UNITED STATES OF AMERICA / US / USA