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Levels of Produced Antibodies after Vaccination with mRNA Vaccine; Effect of Previous Infection with SARS-CoV-2.
Konstantinidis, Theocharis G; Zisaki, Stavroula; Mitroulis, Ioannis; Konstantinidou, Eleni; Kontekaki, Eftychia G; Romanidou, Gioulia; Karvelas, Alexandros; Nanousi, Ioanna; Lazidis, Leonidas; Cassimos, Dimitrios; Tsigalou, Christina; Martinis, Georges; Panopoulou, Maria.
Affiliation
  • Konstantinidis TG; Blood Transfusion Center, University General Hospital of Alexandroupolis Dragana Campus, 68100 Alexandroupolis, Greece.
  • Zisaki S; Laboratory of Microbiology, Democritus University of Thrace, University General Hospital of Alexandroupolis Dragana Campus, 68100 Alexandroupolis, Greece.
  • Mitroulis I; Blood Transfusion Center, University General Hospital of Alexandroupolis Dragana Campus, 68100 Alexandroupolis, Greece.
  • Konstantinidou E; First Department of Internal Medicine, Democritus University of Thrace, 68100 Alexandroupolis, Greece.
  • Kontekaki EG; Blood Transfusion Center, General Hospital of Drama, 66100 Drama, Greece.
  • Romanidou G; Blood Transfusion Center, University General Hospital of Alexandroupolis Dragana Campus, 68100 Alexandroupolis, Greece.
  • Karvelas A; Nephrology Department, General Hospital "Sismanogleio", 69100 Komotini, Greece.
  • Nanousi I; Laboratory of Microbiology, Democritus University of Thrace, University General Hospital of Alexandroupolis Dragana Campus, 68100 Alexandroupolis, Greece.
  • Lazidis L; Blood Transfusion Center, University General Hospital of Alexandroupolis Dragana Campus, 68100 Alexandroupolis, Greece.
  • Cassimos D; Blood Transfusion Center, University General Hospital of Alexandroupolis Dragana Campus, 68100 Alexandroupolis, Greece.
  • Tsigalou C; Pediatric Department, Democritus University of Thrace, 68100 Alexandroupolis, Greece.
  • Martinis G; Laboratory of Microbiology, Democritus University of Thrace, University General Hospital of Alexandroupolis Dragana Campus, 68100 Alexandroupolis, Greece.
  • Panopoulou M; Blood Transfusion Center, University General Hospital of Alexandroupolis Dragana Campus, 68100 Alexandroupolis, Greece.
J Clin Med ; 10(13)2021 Jun 27.
Article in En | MEDLINE | ID: mdl-34199029
ABSTRACT
The aim of this study was to estimate the immunogenic effect of mRNA vaccine against SARS-CoV-2. This study included 510 participants who received mRNA vaccine. The measurement of anti-COVID-19 antibodies was performed using the Abbott SARS-CoV-2 IgG quantitative assay (Abbott). Overall, mean titer of anti-Spike antibodies was 19,319.2 ± 1787.5 AU/mL. Vaccination induced a robust immunogenic response in those previously infected with SARS-CoV-2 compared with non-infected subjects. Additionally, individuals that were asymptomatic after vaccination produced lower levels of antibodies compared to feverish individuals. In conclusion, remarkably high levels of anti-Spike COVID-19 antibodies were observed after vaccination.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: J Clin Med Year: 2021 Document type: Article Affiliation country: Grecia
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Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: J Clin Med Year: 2021 Document type: Article Affiliation country: Grecia