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Safety and immunogenicity of an inactivated SARS-CoV-2 vaccine in healthy adults aged 18 years or older: A randomized, double-blind, placebo-controlled, phase 1/2 trial.
Guo, Wanshen; Duan, Kai; Zhang, Yuntao; Yuan, Zhiming; Zhang, Yan-Bo; Wang, Zejun; Zhao, Dongyang; Zhang, Huajun; Xie, Zhiqiang; Li, Xinguo; Peng, Cheng; Zhang, Wei; Yang, Yunkai; Chen, Wei; Gao, Xiaoxiao; You, Wangyang; Wang, Xue-Wei; Shi, Zhengli; Wang, Yanxia; Yang, Xu-Qin; Zhang, Lianghao; Huang, Lili; Wang, Qian; Lu, Jia; Yang, Yong-Li; Guo, Jing; Zhou, Wei; Wan, Xin; Wu, Cong; Wang, Wenhui; Du, Jianhui; Nian, Xuanxuan; Li, Xing-Hang; Huang, Shihe; Shen, Shuo; Xia, Shengli; Pan, An; Yang, Xiaoming.
Affiliation
  • Guo W; Henan Province Centre for Disease Control and Prevention, Zhengzhou, Henan, China.
  • Duan K; National Engineering Technology Research Centre for Combined Vaccines, Wuhan Institute of Biological Products Co. Ltd., Wuhan, Hubei, China.
  • Zhang Y; China National Biotec Group Company Limited, Beijing, China.
  • Yuan Z; Chinese Academy of Sciences Key Laboratory of Special Pathogens, Wuhan Institute of Virology, Centre for Biosafety Mega-Science, Chinese Academy of Sciences, Wuhan, Hubei, China.
  • Zhang YB; Department of Epidemiology and Biostatistics, Ministry of Education Key Laboratory of Environment and Health and State Key Laboratory of Environmental Health (incubation), School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.
  • Wang Z; National Engineering Technology Research Centre for Combined Vaccines, Wuhan Institute of Biological Products Co. Ltd., Wuhan, Hubei, China.
  • Zhao D; Henan Province Centre for Disease Control and Prevention, Zhengzhou, Henan, China.
  • Zhang H; Chinese Academy of Sciences Key Laboratory of Special Pathogens, Wuhan Institute of Virology, Centre for Biosafety Mega-Science, Chinese Academy of Sciences, Wuhan, Hubei, China.
  • Xie Z; Henan Province Centre for Disease Control and Prevention, Zhengzhou, Henan, China.
  • Li X; National Engineering Technology Research Centre for Combined Vaccines, Wuhan Institute of Biological Products Co. Ltd., Wuhan, Hubei, China.
  • Peng C; Chinese Academy of Sciences Key Laboratory of Special Pathogens, Wuhan Institute of Virology, Centre for Biosafety Mega-Science, Chinese Academy of Sciences, Wuhan, Hubei, China.
  • Zhang W; Henan Province Centre for Disease Control and Prevention, Zhengzhou, Henan, China.
  • Yang Y; China National Biotec Group Company Limited, Beijing, China.
  • Chen W; National Engineering Technology Research Centre for Combined Vaccines, Wuhan Institute of Biological Products Co. Ltd., Wuhan, Hubei, China.
  • Gao X; Chinese Academy of Sciences Key Laboratory of Special Pathogens, Wuhan Institute of Virology, Centre for Biosafety Mega-Science, Chinese Academy of Sciences, Wuhan, Hubei, China.
  • You W; Henan Province Centre for Disease Control and Prevention, Zhengzhou, Henan, China.
  • Wang XW; China National Biotec Group Company Limited, Beijing, China.
  • Shi Z; Chinese Academy of Sciences Key Laboratory of Special Pathogens, Wuhan Institute of Virology, Centre for Biosafety Mega-Science, Chinese Academy of Sciences, Wuhan, Hubei, China.
  • Wang Y; Henan Province Centre for Disease Control and Prevention, Zhengzhou, Henan, China.
  • Yang XQ; China National Biotec Group Company Limited, Beijing, China.
  • Zhang L; National Engineering Technology Research Centre for Combined Vaccines, Wuhan Institute of Biological Products Co. Ltd., Wuhan, Hubei, China.
  • Huang L; Henan Province Centre for Disease Control and Prevention, Zhengzhou, Henan, China.
  • Wang Q; China National Biotec Group Company Limited, Beijing, China.
  • Lu J; National Engineering Technology Research Centre for Combined Vaccines, Wuhan Institute of Biological Products Co. Ltd., Wuhan, Hubei, China.
  • Yang YL; Department of Epidemiology and Biostatistics, College of Public Health, Zhengzhou University, Zhengzhou, Henan, China.
  • Guo J; National Engineering Technology Research Centre for Combined Vaccines, Wuhan Institute of Biological Products Co. Ltd., Wuhan, Hubei, China.
  • Zhou W; National Engineering Technology Research Centre for Combined Vaccines, Wuhan Institute of Biological Products Co. Ltd., Wuhan, Hubei, China.
  • Wan X; National Engineering Technology Research Centre for Combined Vaccines, Wuhan Institute of Biological Products Co. Ltd., Wuhan, Hubei, China.
  • Wu C; National Engineering Technology Research Centre for Combined Vaccines, Wuhan Institute of Biological Products Co. Ltd., Wuhan, Hubei, China.
  • Wang W; National Engineering Technology Research Centre for Combined Vaccines, Wuhan Institute of Biological Products Co. Ltd., Wuhan, Hubei, China.
  • Du J; National Engineering Technology Research Centre for Combined Vaccines, Wuhan Institute of Biological Products Co. Ltd., Wuhan, Hubei, China.
  • Nian X; National Engineering Technology Research Centre for Combined Vaccines, Wuhan Institute of Biological Products Co. Ltd., Wuhan, Hubei, China.
  • Li XH; National Engineering Technology Research Centre for Combined Vaccines, Wuhan Institute of Biological Products Co. Ltd., Wuhan, Hubei, China.
  • Huang S; National Engineering Technology Research Centre for Combined Vaccines, Wuhan Institute of Biological Products Co. Ltd., Wuhan, Hubei, China.
  • Shen S; National Engineering Technology Research Centre for Combined Vaccines, Wuhan Institute of Biological Products Co. Ltd., Wuhan, Hubei, China.
  • Xia S; Henan Province Centre for Disease Control and Prevention, Zhengzhou, Henan, China.
  • Pan A; Department of Epidemiology and Biostatistics, Ministry of Education Key Laboratory of Environment and Health and State Key Laboratory of Environmental Health (incubation), School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.
  • Yang X; National Engineering Technology Research Centre for Combined Vaccines, Wuhan Institute of Biological Products Co. Ltd., Wuhan, Hubei, China.
EClinicalMedicine ; 38: 101010, 2021 Aug.
Article in En | MEDLINE | ID: mdl-34250456
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Full text: 1 Collection: 01-internacional Database: MEDLINE Type of study: Clinical_trials Language: En Journal: EClinicalMedicine Year: 2021 Document type: Article Affiliation country: China Country of publication: Reino Unido
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Full text: 1 Collection: 01-internacional Database: MEDLINE Type of study: Clinical_trials Language: En Journal: EClinicalMedicine Year: 2021 Document type: Article Affiliation country: China Country of publication: Reino Unido