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Gene-Environment Interactions in Developmental Neurotoxicity: a Case Study of Synergy between Chlorpyrifos and CHD8 Knockout in Human BrainSpheres.
Modafferi, Sergio; Zhong, Xiali; Kleensang, Andre; Murata, Yohei; Fagiani, Francesca; Pamies, David; Hogberg, Helena T; Calabrese, Vittorio; Lachman, Herbert; Hartung, Thomas; Smirnova, Lena.
Affiliation
  • Modafferi S; Center for Alternatives to Animal Testing, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland, USA.
  • Zhong X; Department of Biomedical and Biotechnological Sciences, School of Medicine, University of Catania, Catania, Italy.
  • Kleensang A; Center for Alternatives to Animal Testing, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland, USA.
  • Murata Y; Guangdong Provincial Key Laboratory of Food, Nutrition and Health, Department of Toxicology, School of Public Health, Sun Yat-sen University, Guangzhou, China.
  • Fagiani F; Center for Alternatives to Animal Testing, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland, USA.
  • Pamies D; Center for Alternatives to Animal Testing, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland, USA.
  • Hogberg HT; Research Center, Nihon Nohyaku Co. Ltd., Osaka, Japan.
  • Calabrese V; Center for Alternatives to Animal Testing, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland, USA.
  • Lachman H; Department of Drug Sciences, Pharmacology Section, University of Pavia, Pavia, Italy.
  • Hartung T; Istituto Universitario di Studi Superiori (Scuola Universitaria Superiore IUSS) Pavia, Pavia, Italy.
  • Smirnova L; Center for Alternatives to Animal Testing, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland, USA.
Environ Health Perspect ; 129(7): 77001, 2021 07.
Article in En | MEDLINE | ID: mdl-34259569
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Autistic Disorder / Chlorpyrifos / Induced Pluripotent Stem Cells / Autism Spectrum Disorder Type of study: Etiology_studies / Prognostic_studies / Risk_factors_studies Limits: Humans Language: En Journal: Environ Health Perspect Year: 2021 Document type: Article Affiliation country: Estados Unidos Country of publication: Estados Unidos
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Autistic Disorder / Chlorpyrifos / Induced Pluripotent Stem Cells / Autism Spectrum Disorder Type of study: Etiology_studies / Prognostic_studies / Risk_factors_studies Limits: Humans Language: En Journal: Environ Health Perspect Year: 2021 Document type: Article Affiliation country: Estados Unidos Country of publication: Estados Unidos