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Discovery of Selective Small-Molecule Inhibitors for the ENL YEATS Domain.
Ma, Xinyu R; Xu, Longxia; Xu, Shiqing; Klein, Brianna J; Wang, Hongkuan; Das, Sukant; Li, Kuai; Yang, Kai S; Sohail, Sana; Chapman, Andrew; Kutateladze, Tatiana G; Shi, Xiaobing; Liu, Wenshe Ray; Wen, Hong.
Affiliation
  • Ma XR; Texas A&M Drug Discovery Laboratory, Department of Chemistry, Texas A&M University, College Station, Texas 77843, United States.
  • Xu L; Department of Epigenetics, Van Andel Institute, Grand Rapids, Michigan 49503, United States.
  • Xu S; Texas A&M Drug Discovery Laboratory, Department of Chemistry, Texas A&M University, College Station, Texas 77843, United States.
  • Klein BJ; Department of Pharmacology, University of Colorado School of Medicine, Aurora, Colorado 80045, United States.
  • Wang H; Department of Epigenetics, Van Andel Institute, Grand Rapids, Michigan 49503, United States.
  • Das S; Texas A&M Drug Discovery Laboratory, Department of Chemistry, Texas A&M University, College Station, Texas 77843, United States.
  • Li K; Department of Epigenetics, Van Andel Institute, Grand Rapids, Michigan 49503, United States.
  • Yang KS; Texas A&M Drug Discovery Laboratory, Department of Chemistry, Texas A&M University, College Station, Texas 77843, United States.
  • Sohail S; Department of Epigenetics, Van Andel Institute, Grand Rapids, Michigan 49503, United States.
  • Chapman A; Texas A&M Drug Discovery Laboratory, Department of Chemistry, Texas A&M University, College Station, Texas 77843, United States.
  • Kutateladze TG; Department of Pharmacology, University of Colorado School of Medicine, Aurora, Colorado 80045, United States.
  • Shi X; Department of Epigenetics, Van Andel Institute, Grand Rapids, Michigan 49503, United States.
  • Liu WR; Texas A&M Drug Discovery Laboratory, Department of Chemistry, Texas A&M University, College Station, Texas 77843, United States.
  • Wen H; Institute of Biosciences and Technology and Department of Translational Medical Sciences, College of Medicine, Texas A&M University, Houston, Texas 77030, United States.
J Med Chem ; 64(15): 10997-11013, 2021 08 12.
Article in En | MEDLINE | ID: mdl-34279931
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Leukemia, Myeloid, Acute / Transcriptional Elongation Factors / Small Molecule Libraries / Drug Discovery / Antineoplastic Agents Type of study: Prognostic_studies Limits: Humans Language: En Journal: J Med Chem Journal subject: QUIMICA Year: 2021 Document type: Article Affiliation country: Estados Unidos
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Leukemia, Myeloid, Acute / Transcriptional Elongation Factors / Small Molecule Libraries / Drug Discovery / Antineoplastic Agents Type of study: Prognostic_studies Limits: Humans Language: En Journal: J Med Chem Journal subject: QUIMICA Year: 2021 Document type: Article Affiliation country: Estados Unidos