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Novel RAF/MEK inhibitor CH5126766/VS-6766 has efficacy in combination with eribulin for the treatment of triple-negative breast cancer.
Ono, Hisako; Horinaka, Mano; Sukeno, Mamiko; Morita, Mie; Yasuda, Shusuke; Nishimoto, Emi; Konishi, Eiichi; Sakai, Toshiyuki.
Affiliation
  • Ono H; Department of Molecular Diagnostics and Therapeutics, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan.
  • Horinaka M; Department of Endocrine and Breast Surgery, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan.
  • Sukeno M; Department of Drug Discovery Medicine, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan.
  • Morita M; Department of Drug Discovery Medicine, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan.
  • Yasuda S; Department of Drug Discovery Medicine, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan.
  • Nishimoto E; Department of Drug Discovery Medicine, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan.
  • Konishi E; Department of Drug Discovery Medicine, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan.
  • Sakai T; Department of Drug Discovery Medicine, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan.
Cancer Sci ; 112(10): 4166-4175, 2021 Oct.
Article in En | MEDLINE | ID: mdl-34288272
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Antineoplastic Combined Chemotherapy Protocols / Proto-Oncogene Proteins c-raf / Coumarins / Mitogen-Activated Protein Kinase Kinases / Protein Kinase Inhibitors / Triple Negative Breast Neoplasms / Furans / Ketones Limits: Animals Language: En Journal: Cancer Sci Year: 2021 Document type: Article Affiliation country: Japón
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Antineoplastic Combined Chemotherapy Protocols / Proto-Oncogene Proteins c-raf / Coumarins / Mitogen-Activated Protein Kinase Kinases / Protein Kinase Inhibitors / Triple Negative Breast Neoplasms / Furans / Ketones Limits: Animals Language: En Journal: Cancer Sci Year: 2021 Document type: Article Affiliation country: Japón