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Safety and efficacy of itepekimab in patients with moderate-to-severe COPD: a genetic association study and randomised, double-blind, phase 2a trial.
Rabe, Klaus F; Celli, Bartolome R; Wechsler, Michael E; Abdulai, Raolat M; Luo, Xiaodong; Boomsma, Maarten M; Staudinger, Heribert; Horowitz, Julie E; Baras, Aris; Ferreira, Manuel A; Ruddy, Marcella K; Nivens, Michael C; Amin, Nikhil; Weinreich, David M; Yancopoulos, George D; Goulaouic, Helene.
Affiliation
  • Rabe KF; LungenClinic Grosshansdorf, Grosshansdorf, Germany; Christian Albrechts University of Kiel, Airway Research Center North, German Center for Lung Research, Grosshansdorf, Germany. Electronic address: k.f.rabe@lungenclinic.de.
  • Celli BR; Pulmonary and Critical Care Division, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.
  • Wechsler ME; Department of Medicine, National Jewish Health, Denver, CO, USA.
  • Abdulai RM; Sanofi, Cambridge, MA, USA.
  • Luo X; Sanofi, Bridgewater, NJ, USA.
  • Boomsma MM; Sanofi, Amsterdam, Netherlands.
  • Staudinger H; Sanofi, Bridgewater, NJ, USA.
  • Horowitz JE; Regeneron Pharmaceuticals, Tarrytown, NY, USA.
  • Baras A; Regeneron Pharmaceuticals, Tarrytown, NY, USA.
  • Ferreira MA; Regeneron Pharmaceuticals, Tarrytown, NY, USA.
  • Ruddy MK; Regeneron Pharmaceuticals, Tarrytown, NY, USA.
  • Nivens MC; Regeneron Pharmaceuticals, Tarrytown, NY, USA.
  • Amin N; Regeneron Pharmaceuticals, Tarrytown, NY, USA.
  • Weinreich DM; Regeneron Pharmaceuticals, Tarrytown, NY, USA.
  • Yancopoulos GD; Regeneron Pharmaceuticals, Tarrytown, NY, USA.
  • Goulaouic H; Sanofi, Chilly-Mazarin, France.
Lancet Respir Med ; 9(11): 1288-1298, 2021 11.
Article in En | MEDLINE | ID: mdl-34302758
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Anti-Asthmatic Agents / Pulmonary Disease, Chronic Obstructive Type of study: Clinical_trials / Etiology_studies / Prognostic_studies / Risk_factors_studies Limits: Adult / Aged / Humans / Middle aged Language: En Journal: Lancet Respir Med Year: 2021 Document type: Article Country of publication: Reino Unido
Fulltext
Add to My VHL
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Anti-Asthmatic Agents / Pulmonary Disease, Chronic Obstructive Type of study: Clinical_trials / Etiology_studies / Prognostic_studies / Risk_factors_studies Limits: Adult / Aged / Humans / Middle aged Language: En Journal: Lancet Respir Med Year: 2021 Document type: Article Country of publication: Reino Unido