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BK virus-specific T cells for immunotherapy of progressive multifocal leukoencephalopathy: an open-label, single-cohort pilot study.
Cortese, Irene; Beck, Erin S; Al-Louzi, Omar; Ohayon, Joan; Andrada, Frances; Osuorah, Ikesinachi; Dwyer, Jenifer; Billioux, B Jeanne; Dargah-Zada, Nigar; Schindler, Matthew K; Binder, Kyle; Reoma, Lauren; Norato, Gina; Enose-Akahata, Yoshimi; Smith, Bryan R; Monaco, Maria Chiara; Major, Eugene O; Jacobson, Steven; Stroncek, David; Highfill, Steven; Panch, Sandhya; Reich, Daniel S; Barrett, John; Nath, Avindra; Muranski, Pawel.
Affiliation
  • Cortese I; Neuroimmunology Clinic, National Institutes of Health, Bethesda, MD, USA. Electronic address: corteseir@ninds.nih.gov.
  • Beck ES; Translational Neuroradiology Section, National Institutes of Health, Bethesda, MD, USA.
  • Al-Louzi O; Translational Neuroradiology Section, National Institutes of Health, Bethesda, MD, USA.
  • Ohayon J; Neuroimmunology Clinic, National Institutes of Health, Bethesda, MD, USA.
  • Andrada F; Neuroimmunology Clinic, National Institutes of Health, Bethesda, MD, USA.
  • Osuorah I; Neuroimmunology Clinic, National Institutes of Health, Bethesda, MD, USA.
  • Dwyer J; Neuroimmunology Clinic, National Institutes of Health, Bethesda, MD, USA.
  • Billioux BJ; Viral Immunology Section, National Institutes of Health, Bethesda, MD, USA.
  • Dargah-Zada N; Neuroimmunology Clinic, National Institutes of Health, Bethesda, MD, USA.
  • Schindler MK; Translational Neuroradiology Section, National Institutes of Health, Bethesda, MD, USA.
  • Binder K; National Institute of Neurological Disorders and Stroke, and Molecular Development of the Immune System Section, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.
  • Reoma L; Clinical Trials Unit, National Institutes of Health, Bethesda, MD, USA.
  • Norato G; Clinical Trials Unit, National Institutes of Health, Bethesda, MD, USA.
  • Enose-Akahata Y; Viral Immunology Section, National Institutes of Health, Bethesda, MD, USA.
  • Smith BR; Section of Infections of the Nervous System, National Institutes of Health, Bethesda, MD, USA.
  • Monaco MC; Laboratory of Molecular Medicine and Neuroscience, National Institutes of Health, Bethesda, MD, USA.
  • Major EO; Laboratory of Molecular Medicine and Neuroscience, National Institutes of Health, Bethesda, MD, USA.
  • Jacobson S; Viral Immunology Section, National Institutes of Health, Bethesda, MD, USA.
  • Stroncek D; Center for Cellular Engineering, Department of Transfusion Medicine, National Institutes of Health, Bethesda, MD, USA.
  • Highfill S; Center for Cellular Engineering, Department of Transfusion Medicine, National Institutes of Health, Bethesda, MD, USA.
  • Panch S; Center for Cellular Engineering, Department of Transfusion Medicine, National Institutes of Health, Bethesda, MD, USA.
  • Reich DS; Translational Neuroradiology Section, National Institutes of Health, Bethesda, MD, USA.
  • Barrett J; Hematology Branch, Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA; George Washington University Cancer Center, George Washington University, Washington, DC, USA.
  • Nath A; Section of Infections of the Nervous System, National Institutes of Health, Bethesda, MD, USA.
  • Muranski P; Hematology Branch, Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA; Herbert Irving Comprehensive Cancer Center, Columbia University Medical Center, New York, NY, USA.
Lancet Neurol ; 20(8): 639-652, 2021 08.
Article in En | MEDLINE | ID: mdl-34302788

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: T-Lymphocytes / Leukoencephalopathy, Progressive Multifocal / BK Virus / Immunotherapy Type of study: Etiology_studies / Incidence_studies / Observational_studies / Risk_factors_studies Limits: Adult / Aged / Female / Humans / Male / Middle aged Language: En Journal: Lancet Neurol Journal subject: NEUROLOGIA Year: 2021 Document type: Article Country of publication: Reino Unido

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: T-Lymphocytes / Leukoencephalopathy, Progressive Multifocal / BK Virus / Immunotherapy Type of study: Etiology_studies / Incidence_studies / Observational_studies / Risk_factors_studies Limits: Adult / Aged / Female / Humans / Male / Middle aged Language: En Journal: Lancet Neurol Journal subject: NEUROLOGIA Year: 2021 Document type: Article Country of publication: Reino Unido