Novologue Therapy Requires Heat Shock Protein 70 and Thioredoxin-Interacting Protein to Improve Mitochondrial Bioenergetics and Decrease Mitophagy in Diabetic Sensory Neurons.

Rodriguez, Yssa A; Kaur, Sukmanjit; Nolte, Erika; Zheng, Zhang; Blagg, Brian S J; Dobrowsky, Rick T

Rodriguez, Yssa A; Kaur, Sukmanjit; Nolte, Erika; Zheng, Zhang; Blagg, Brian S J; Dobrowsky, Rick T.

Affiliation

Rodriguez YA; Department of Pharmacology and Toxicology, University of Kansas, 5064 Malott Hall/1251 Wescoe Hall Drive, Lawrence, Kansas 66045, United States.
Kaur S; Department of Pharmacology and Toxicology, University of Kansas, 5064 Malott Hall/1251 Wescoe Hall Drive, Lawrence, Kansas 66045, United States.
Nolte E; Department of Pharmacology and Toxicology, University of Kansas, 5064 Malott Hall/1251 Wescoe Hall Drive, Lawrence, Kansas 66045, United States.
Zheng Z; Department of Chemistry and Biochemistry University of Notre Dame, 305 McCourtney Hall, Notre Dame, Indiana 46556, United States.
Blagg BSJ; Department of Chemistry and Biochemistry University of Notre Dame, 305 McCourtney Hall, Notre Dame, Indiana 46556, United States.
Dobrowsky RT; Department of Pharmacology and Toxicology, University of Kansas, 5064 Malott Hall/1251 Wescoe Hall Drive, Lawrence, Kansas 66045, United States.

ACS Chem Neurosci ; 12(16): 3049-3059, 2021 08 18.

Article in En | MEDLINE | ID: mdl-34340312

Subject(s)
Key words

C-terminal Hsp90 modulator; diabetic peripheral neuropathy; molecular chaperones; neuroprotection; novologues; sensory neuron

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Diabetes Mellitus / Diabetic Neuropathies Limits: Animals Language: En Journal: ACS Chem Neurosci Year: 2021 Document type: Article Affiliation country: Estados Unidos Country of publication: Estados Unidos

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