Role of Physical Activity and Cardiac Rehabilitation in Patients Undergoing Hematopoietic Stem Cell Transplantation.
JACC CardioOncol
; 3(1): 17-34, 2021 Mar.
Article
in En
| MEDLINE
| ID: mdl-34396304
ABSTRACT
Hematopoietic stem cell transplantation (HSCT) is a standard treatment for several malignancies, and >50,000 HSCT are performed annually worldwide. As survival after HSCT improves, cardiovascular disease and associated risk factors have gained importance as a significant cause of morbidity and mortality in this cohort. In this article, we detail the risk factors for cardiovascular disease and their impact in patients undergoing HSCT. Additionally, we critically review the data on the impact of physical exercise in patients undergoing HSCT. Although limited by significant heterogeneity in methodologies, small sample sizes, attrition, and lack of long-term cardiovascular follow-up, most of these studies reinforce the beneficial effects of physical activity and exercise in this patient population. Cardiac rehabilitation (CR) is a structured exercise and lifestyle modification program that is typically instituted in patients who experience acute cardiovascular events. We review the data on CR in the oncologic and nononcologic populations with an aim of building a framework for use of CR in HSCT patients.
ACSM, American College of Sports Medicine; AHA, American Heart Association; CR, cardiac rehabilitation; CVD, cardiovascular disease; GVHD, graft-versus-host disease; HSCT, hematopoietic stem cell transplantation; MFI, Multidimensional Fatigue Inventory; MI, myocardial infarction; PCI, percutaneous coronary interventions; Vo2max, maximal oxygen consumption; cardiac rehabilitation; hematopoietic stem cell transplantation
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Language:
En
Journal:
JACC CardioOncol
Year:
2021
Document type:
Article
Affiliation country:
Estados Unidos