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Development and Preclinical Evaluation of Radiolabeled Covalent G12C-Specific Inhibitors for Direct Imaging of the Oncogenic KRAS Mutant.
Zhang, Zhe; Wang, Xiaobo; Ye, Jiajun; Liu, Huanhuan; Fang, Jianyang; Zhang, Mingru; Li, Yesen; Huang, Jinxiong; Zhang, Deliang; Wang, Jing; Zhang, Xianzhong.
Affiliation
  • Zhang Z; Center for Molecular Imaging and Translational Medicine, State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, School of Public Health, Xiamen University, Xiamen 361102, China.
  • Wang X; Center for Molecular Imaging and Translational Medicine, State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, School of Public Health, Xiamen University, Xiamen 361102, China.
  • Ye J; Department of Nuclear Medicine, Xijing Hospital, Fourth Military Medical University, Xi'an 710032, China.
  • Liu H; Center for Molecular Imaging and Translational Medicine, State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, School of Public Health, Xiamen University, Xiamen 361102, China.
  • Fang J; Center for Molecular Imaging and Translational Medicine, State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, School of Public Health, Xiamen University, Xiamen 361102, China.
  • Zhang M; Department of Nuclear Medicine, Xijing Hospital, Fourth Military Medical University, Xi'an 710032, China.
  • Li Y; Department of Nuclear Medicine & Minnan PET Center, The First Affiliated Hospital of Xiamen University, Xiamen 361003, China.
  • Huang J; Department of Nuclear Medicine & Minnan PET Center, The First Affiliated Hospital of Xiamen University, Xiamen 361003, China.
  • Zhang D; Center for Molecular Imaging and Translational Medicine, State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, School of Public Health, Xiamen University, Xiamen 361102, China.
  • Wang J; Department of Nuclear Medicine, Xijing Hospital, Fourth Military Medical University, Xi'an 710032, China.
  • Zhang X; Center for Molecular Imaging and Translational Medicine, State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, School of Public Health, Xiamen University, Xiamen 361102, China.
Mol Pharm ; 18(9): 3509-3518, 2021 09 06.
Article in En | MEDLINE | ID: mdl-34410132
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Piperazines / Quinazolines / Proto-Oncogene Proteins p21(ras) / Radiopharmaceuticals / Protein Kinase Inhibitors / Neoplasms Type of study: Prognostic_studies Limits: Animals / Female / Humans Language: En Journal: Mol Pharm Journal subject: BIOLOGIA MOLECULAR / FARMACIA / FARMACOLOGIA Year: 2021 Document type: Article Affiliation country: China Country of publication: Estados Unidos
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Piperazines / Quinazolines / Proto-Oncogene Proteins p21(ras) / Radiopharmaceuticals / Protein Kinase Inhibitors / Neoplasms Type of study: Prognostic_studies Limits: Animals / Female / Humans Language: En Journal: Mol Pharm Journal subject: BIOLOGIA MOLECULAR / FARMACIA / FARMACOLOGIA Year: 2021 Document type: Article Affiliation country: China Country of publication: Estados Unidos