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Quantitative Systems Pharmacology Modeling of Avadomide-Induced Neutropenia Enables Virtual Clinical Dose and Schedule Finding Studies.
Abbiati, Roberto A; Pourdehnad, Michael; Carrancio, Soraya; Pierce, Daniel W; Kasibhatla, Shailaja; McConnell, Mark; Trotter, Matthew W B; Loos, Remco; Santini, Cristina C; Ratushny, Alexander V.
Affiliation
  • Abbiati RA; Bristol Myers Squibb, Center for Innovation and Translational Research Europe (CITRE), Seville, Spain. roberto.abbiati@bms.com.
  • Pourdehnad M; Bristol Myers Squibb, San Francisco, California, USA.
  • Carrancio S; Bristol Myers Squibb, San Diego, California, USA.
  • Pierce DW; Bristol Myers Squibb, San Diego, California, USA.
  • Kasibhatla S; Bristol Myers Squibb, San Diego, California, USA.
  • McConnell M; Bristol Myers Squibb, Seattle, Washington, USA.
  • Trotter MWB; Bristol Myers Squibb, Center for Innovation and Translational Research Europe (CITRE), Seville, Spain.
  • Loos R; Bristol Myers Squibb, Center for Innovation and Translational Research Europe (CITRE), Seville, Spain.
  • Santini CC; Roche Pharma Research and Early Development, Pharmaceutical Sciences, Roche Innovation Center, Basel, Switzerland.
  • Ratushny AV; Bristol Myers Squibb, Seattle, Washington, USA. alexander.ratushnyy@bms.com.
AAPS J ; 23(5): 103, 2021 08 27.
Article in En | MEDLINE | ID: mdl-34453265
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Piperidones / Quinazolinones / Models, Biological / Neutropenia / Antineoplastic Agents Type of study: Diagnostic_studies / Prognostic_studies Limits: Humans Language: En Journal: AAPS J Journal subject: FARMACOLOGIA / TERAPIA POR MEDICAMENTOS Year: 2021 Document type: Article Affiliation country: España Country of publication: Estados Unidos
Fulltext
Add to My VHL
Print
XML
PubMed Links
Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Piperidones / Quinazolinones / Models, Biological / Neutropenia / Antineoplastic Agents Type of study: Diagnostic_studies / Prognostic_studies Limits: Humans Language: En Journal: AAPS J Journal subject: FARMACOLOGIA / TERAPIA POR MEDICAMENTOS Year: 2021 Document type: Article Affiliation country: España Country of publication: Estados Unidos