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Applicability of cerebral open flow microperfusion and microdialysis to quantify a brain-penetrating nanobody in mice.
Custers, Marie-Laure; Wouters, Yessica; Jaspers, Tom; De Bundel, Dimitri; Dewilde, Maarten; Van Eeckhaut, Ann; Smolders, Ilse.
Affiliation
  • Custers ML; Vrije Universiteit Brussel (VUB), Department of Pharmaceutical Chemistry, Drug Analysis and Drug Information, Research Group Experimental Pharmacology, Center for Neurosciences (C4N), Laarbeeklaan 103, 1090 Brussels, Belgium. Electronic address: Marie-Laure.Custers@vub.be.
  • Wouters Y; VIB Center for Brain & Disease Research, Campus Gasthuisberg O&N4, Herestraat 49, Box 602, 3000 Leuven, Belgium; Laboratory for the Research of Neurodegenerative Diseases, Department of Neurosciences, Leuven Brain Institute (LBI), KU Leuven, 3000 Leuven, Belgium. Electronic address: yessica.
  • Jaspers T; VIB Center for Brain & Disease Research, Campus Gasthuisberg O&N4, Herestraat 49, Box 602, 3000 Leuven, Belgium; Laboratory for the Research of Neurodegenerative Diseases, Department of Neurosciences, Leuven Brain Institute (LBI), KU Leuven, 3000 Leuven, Belgium. Electronic address: tom.jasp
  • De Bundel D; Vrije Universiteit Brussel (VUB), Department of Pharmaceutical Chemistry, Drug Analysis and Drug Information, Research Group Experimental Pharmacology, Center for Neurosciences (C4N), Laarbeeklaan 103, 1090 Brussels, Belgium. Electronic address: Dimitri.De.Bundel@vub.be.
  • Dewilde M; VIB Center for Brain & Disease Research, Campus Gasthuisberg O&N4, Herestraat 49, Box 602, 3000 Leuven, Belgium; Laboratory for the Research of Neurodegenerative Diseases, Department of Neurosciences, Leuven Brain Institute (LBI), KU Leuven, 3000 Leuven, Belgium. Electronic address: maarten.
  • Van Eeckhaut A; Vrije Universiteit Brussel (VUB), Department of Pharmaceutical Chemistry, Drug Analysis and Drug Information, Research Group Experimental Pharmacology, Center for Neurosciences (C4N), Laarbeeklaan 103, 1090 Brussels, Belgium. Electronic address: aveeckha@vub.be.
  • Smolders I; Vrije Universiteit Brussel (VUB), Department of Pharmaceutical Chemistry, Drug Analysis and Drug Information, Research Group Experimental Pharmacology, Center for Neurosciences (C4N), Laarbeeklaan 103, 1090 Brussels, Belgium. Electronic address: Ilse.Smolders@vub.be.
Anal Chim Acta ; 1178: 338803, 2021 Sep 15.
Article in En | MEDLINE | ID: mdl-34482878
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Brain / Blood-Brain Barrier Limits: Animals / Humans Language: En Journal: Anal Chim Acta Year: 2021 Document type: Article Country of publication: Países Bajos
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Brain / Blood-Brain Barrier Limits: Animals / Humans Language: En Journal: Anal Chim Acta Year: 2021 Document type: Article Country of publication: Países Bajos