Growth Factors, Reactive Oxygen Species, and Metformin-Promoters of the Wound Healing Process in Burns?
Int J Mol Sci
; 22(17)2021 Sep 01.
Article
in En
| MEDLINE
| ID: mdl-34502429
ABSTRACT
Burns can be caused by various factors and have an increased risk of infection that can seriously delay the wound healing process. Chronic wounds caused by burns represent a major health problem. Wound healing is a complex process, orchestrated by cytokines, growth factors, prostaglandins, free radicals, clotting factors, and nitric oxide. Growth factors released during this process are involved in cell growth, proliferation, migration, and differentiation. Reactive oxygen species are released in acute and chronic burn injuries and play key roles in healing and regeneration. The main aim of this review is to present the roles of growth factors, reactive oxygen species, and metformin in the healing process of burn injuries.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Wound Healing
/
Burns
/
Reactive Oxygen Species
/
Intercellular Signaling Peptides and Proteins
/
Metformin
Limits:
Animals
/
Humans
Language:
En
Journal:
Int J Mol Sci
Year:
2021
Document type:
Article
Affiliation country:
Rumanía