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The self-assembled nanoparticle-based trimeric RBD mRNA vaccine elicits robust and durable protective immunity against SARS-CoV-2 in mice.
Sun, Wenqiang; He, Lihong; Zhang, He; Tian, Xiaodong; Bai, Zhihua; Sun, Lei; Yang, Limin; Jia, Xiaojuan; Bi, Yuhai; Luo, Tingrong; Cheng, Gong; Fan, Wenhui; Liu, Wenjun; Li, Jing.
Affiliation
  • Sun W; CAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing, China.
  • He L; Institute of Infectious Diseases, Shenzhen Bay Laboratory, Shenzhen, Guangdong, China.
  • Zhang H; State Key Laboratory for Conservation and Utilization of Subtropical Agro-Bioresources & Laboratory of Animal Infectious Diseases, College of Animal Sciences and Veterinary Medicine, Guangxi University, Nanning, Guangxi, China.
  • Tian X; CAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing, China.
  • Bai Z; University of Chinese Academy of Sciences, Beijing, China.
  • Sun L; CAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing, China.
  • Yang L; Institute of Infectious Diseases, Shenzhen Bay Laboratory, Shenzhen, Guangdong, China.
  • Jia X; CAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing, China.
  • Bi Y; CAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing, China.
  • Luo T; University of Chinese Academy of Sciences, Beijing, China.
  • Cheng G; CAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing, China.
  • Fan W; University of Chinese Academy of Sciences, Beijing, China.
  • Liu W; CAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing, China.
  • Li J; CAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing, China.
Signal Transduct Target Ther ; 6(1): 340, 2021 09 09.
Article in En | MEDLINE | ID: mdl-34504054
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Vaccines, Synthetic / Nanoparticles / COVID-19 Vaccines / SARS-CoV-2 / COVID-19 Limits: Animals / Female / Humans Language: En Journal: Signal Transduct Target Ther Year: 2021 Document type: Article Affiliation country: China Country of publication: Reino Unido
Fulltext
Add to My VHL
Print
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Vaccines, Synthetic / Nanoparticles / COVID-19 Vaccines / SARS-CoV-2 / COVID-19 Limits: Animals / Female / Humans Language: En Journal: Signal Transduct Target Ther Year: 2021 Document type: Article Affiliation country: China Country of publication: Reino Unido