Fenofibrate inhibits hypoxia-inducible factor-1 alpha and carbonic anhydrase expression through activation of AMP-activated protein kinase/HO-1/Sirt1 pathway in glioblastoma cells.

Lin, Chingju; Lai, Sheng-Wei; Shen, Ching-Kai; Chen, Chao-Wei; Tsai, Cheng-Fang; Liu, Yu-Shu; Lu, Dah-Yuu; Huang, Bor-Ren

Lin, Chingju; Lai, Sheng-Wei; Shen, Ching-Kai; Chen, Chao-Wei; Tsai, Cheng-Fang; Liu, Yu-Shu; Lu, Dah-Yuu; Huang, Bor-Ren.

Affiliation

Lin C; Department of Physiology, School of Medicine, China Medical University, Taichung, Taiwan.
Lai SW; Department of Pharmacology, School of Medicine, China Medical University, Taichung, Taiwan.
Shen CK; Graduate Institute of Biomedical Science, China Medical University, Taichung, Taiwan.
Chen CW; Institute of New Drug Development, China Medical University, Taichung, Taiwan.
Tsai CF; Department of Medical Laboratory Science and Biotechnology, Asia University, Taichung, Taiwan.
Liu YS; Department of Pharmacology, School of Medicine, China Medical University, Taichung, Taiwan.
Lu DY; Department of Pharmacology, School of Medicine, China Medical University, Taichung, Taiwan.
Huang BR; Department of Photonics and Communication Engineering, Asia University, Taichung, Taiwan.

Environ Toxicol ; 36(12): 2551-2561, 2021 Dec.

Article in En | MEDLINE | ID: mdl-34520103

Subject(s)
Key words

HIF-1α; HO-1; SIRT1; fenofibrate; glioblastoma

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Fenofibrate / Carbonic Anhydrases / Glioblastoma Limits: Humans Language: En Journal: Environ Toxicol Journal subject: SAUDE AMBIENTAL / TOXICOLOGIA Year: 2021 Document type: Article Affiliation country: Taiwán Country of publication: Estados Unidos

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google