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Ligand-based rational design, synthesis and evaluation of novel potential chemical chaperones for opsin.
Pasqualetto, Gaia; Pileggi, Elisa; Schepelmann, Martin; Varricchio, Carmine; Rozanowska, Malgorzata; Brancale, Andrea; Bassetto, Marcella.
Affiliation
  • Pasqualetto G; School of Pharmacy and Pharmaceutical Sciences, Cardiff University, Cardiff, CF10 3NB, UK.
  • Pileggi E; School of Pharmacy and Pharmaceutical Sciences, Cardiff University, Cardiff, CF10 3NB, UK.
  • Schepelmann M; Institute of Pathophysiology and Allergy Research, Medical University of Vienna, Vienna, 1090, Austria; School of Optometry and Vision Sciences, Cardiff University, Cardiff, CF24 4HQ, UK.
  • Varricchio C; School of Pharmacy and Pharmaceutical Sciences, Cardiff University, Cardiff, CF10 3NB, UK.
  • Rozanowska M; School of Optometry and Vision Sciences, Cardiff University, Cardiff, CF24 4HQ, UK; Cardiff Institute for Tissue Engineering and Repair (CITER), Cardiff University, Cardiff, CF10 3NB, UK.
  • Brancale A; School of Pharmacy and Pharmaceutical Sciences, Cardiff University, Cardiff, CF10 3NB, UK.
  • Bassetto M; Department of Chemistry, Faculty of Science and Engineering, Swansea University, Swansea, SA2 8PP, UK. Electronic address: marcella.bassetto@swansea.ac.uk.
Eur J Med Chem ; 226: 113841, 2021 Dec 15.
Article in En | MEDLINE | ID: mdl-34555613
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Drug Design / Retinitis Pigmentosa / Molecular Chaperones / Opsins / Leber Congenital Amaurosis Limits: Humans Language: En Journal: Eur J Med Chem Year: 2021 Document type: Article Affiliation country: Reino Unido
Fulltext
Add to My VHL
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XML
PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Drug Design / Retinitis Pigmentosa / Molecular Chaperones / Opsins / Leber Congenital Amaurosis Limits: Humans Language: En Journal: Eur J Med Chem Year: 2021 Document type: Article Affiliation country: Reino Unido