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A regulatory phosphorylation site on Mec1 controls chromatin occupancy of RNA polymerases during replication stress.
Hurst, Verena; Challa, Kiran; Jonas, Felix; Forey, Romain; Sack, Ragna; Seebacher, Jan; Schmid, Christoph D; Barkai, Naama; Shimada, Kenji; Gasser, Susan M; Poli, Jérôme.
Affiliation
  • Hurst V; Friedrich Miescher Institute for Biomedical Research, Basel, Switzerland.
  • Challa K; Faculty of Natural Sciences, University of Basel, Basel, Switzerland.
  • Jonas F; Friedrich Miescher Institute for Biomedical Research, Basel, Switzerland.
  • Forey R; Departments of Molecular Genetics and Physics of Complex Systems, Weizmann Institute of Science, Rehovot, Israel.
  • Sack R; Institut de Génétique Humaine, CNRS, Université de Montpellier, Equipe labélisée Ligue contre le Cancer, Montpellier, France.
  • Seebacher J; Friedrich Miescher Institute for Biomedical Research, Basel, Switzerland.
  • Schmid CD; Friedrich Miescher Institute for Biomedical Research, Basel, Switzerland.
  • Barkai N; Friedrich Miescher Institute for Biomedical Research, Basel, Switzerland.
  • Shimada K; Departments of Molecular Genetics and Physics of Complex Systems, Weizmann Institute of Science, Rehovot, Israel.
  • Gasser SM; Friedrich Miescher Institute for Biomedical Research, Basel, Switzerland.
  • Poli J; Friedrich Miescher Institute for Biomedical Research, Basel, Switzerland.
EMBO J ; 40(21): e108439, 2021 11 02.
Article in En | MEDLINE | ID: mdl-34569643
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: RNA Polymerase II / RNA Polymerase III / Protein Processing, Post-Translational / Protein Serine-Threonine Kinases / Saccharomyces cerevisiae Proteins / Intracellular Signaling Peptides and Proteins / DNA Replication Type of study: Prognostic_studies Language: En Journal: EMBO J Year: 2021 Document type: Article Affiliation country: Suiza Country of publication: Reino Unido
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: RNA Polymerase II / RNA Polymerase III / Protein Processing, Post-Translational / Protein Serine-Threonine Kinases / Saccharomyces cerevisiae Proteins / Intracellular Signaling Peptides and Proteins / DNA Replication Type of study: Prognostic_studies Language: En Journal: EMBO J Year: 2021 Document type: Article Affiliation country: Suiza Country of publication: Reino Unido