Host Antiviral Responses against Avian Infectious Bronchitis Virus (IBV): Focus on Innate Immunity.
Viruses
; 13(9)2021 08 26.
Article
in En
| MEDLINE
| ID: mdl-34578280
ABSTRACT
Avian infectious bronchitis virus (IBV) is an important gammacoronavirus. The virus is highly contagious, can infect chickens of all ages, and causes considerable economic losses in the poultry industry worldwide. In the last few decades, numerous studies have been published regarding pathogenicity, vaccination, and host immunity-virus interaction. In particular, innate immunity serves as the first line of defense against invasive pathogens and plays an important role in the pathogenetic process of IBV infection. This review focuses on fundamental aspects of host innate immune responses after IBV infection, including identification of conserved viral structures and different components of host with antiviral activity, which could provide useful information for novel vaccine development, vaccination strategies, and intervention programs.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Poultry Diseases
/
Coronavirus Infections
/
Infectious bronchitis virus
/
Host-Pathogen Interactions
/
Immunity, Innate
Limits:
Animals
Language:
En
Journal:
Viruses
Year:
2021
Document type:
Article
Affiliation country:
China