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DNA hypomethylation leads to cGAS-induced autoinflammation in the epidermis.
Beck, Mirjam A; Fischer, Heinz; Grabner, Lisa M; Groffics, Tamara; Winter, Mircea; Tangermann, Simone; Meischel, Tina; Zaussinger-Haas, Barbara; Wagner, Patrick; Fischer, Carina; Folie, Christina; Arand, Julia; Schöfer, Christian; Ramsahoye, Bernard; Lagger, Sabine; Machat, Georg; Eisenwort, Gregor; Schneider, Stephanie; Podhornik, Alexandra; Kothmayer, Michael; Reichart, Ursula; Glösmann, Martin; Tamir, Ido; Mildner, Michael; Sheibani-Tezerji, Raheleh; Kenner, Lukas; Petzelbauer, Peter; Egger, Gerda; Sibilia, Maria; Ablasser, Andrea; Seiser, Christian.
Affiliation
  • Beck MA; Division of Cell and Developmental Biology, Center for Anatomy and Cell Biology, Medical University of Vienna, Vienna, Austria.
  • Fischer H; Division of Cell and Developmental Biology, Center for Anatomy and Cell Biology, Medical University of Vienna, Vienna, Austria.
  • Grabner LM; Division of Cell and Developmental Biology, Center for Anatomy and Cell Biology, Medical University of Vienna, Vienna, Austria.
  • Groffics T; Division of Cell and Developmental Biology, Center for Anatomy and Cell Biology, Medical University of Vienna, Vienna, Austria.
  • Winter M; Division of Cell and Developmental Biology, Center for Anatomy and Cell Biology, Medical University of Vienna, Vienna, Austria.
  • Tangermann S; Unit of Laboratory Animal Pathology, University of Veterinary Medicine, Vienna, Austria.
  • Meischel T; Division of Cell and Developmental Biology, Center for Anatomy and Cell Biology, Medical University of Vienna, Vienna, Austria.
  • Zaussinger-Haas B; Division of Cell and Developmental Biology, Center for Anatomy and Cell Biology, Medical University of Vienna, Vienna, Austria.
  • Wagner P; Division of Cell and Developmental Biology, Center for Anatomy and Cell Biology, Medical University of Vienna, Vienna, Austria.
  • Fischer C; Division of Cell and Developmental Biology, Center for Anatomy and Cell Biology, Medical University of Vienna, Vienna, Austria.
  • Folie C; Division of Cell and Developmental Biology, Center for Anatomy and Cell Biology, Medical University of Vienna, Vienna, Austria.
  • Arand J; Spinal Cord Injury and Tissue Regeneration Center Salzburg (SCI-TReCS), Salzburg, Austria.
  • Schöfer C; Division of Cell and Developmental Biology, Center for Anatomy and Cell Biology, Medical University of Vienna, Vienna, Austria.
  • Ramsahoye B; Division of Cell and Developmental Biology, Center for Anatomy and Cell Biology, Medical University of Vienna, Vienna, Austria.
  • Lagger S; MRC Institute of Genetics & Molecular Medicine, Centre for Genomic & Experimental Medicine, University of Edinburgh, Edinburgh, UK.
  • Machat G; Unit of Laboratory Animal Pathology, University of Veterinary Medicine, Vienna, Austria.
  • Eisenwort G; Division of Cell and Developmental Biology, Center for Anatomy and Cell Biology, Medical University of Vienna, Vienna, Austria.
  • Schneider S; Institute of Immunology, Medical University of Vienna, Vienna, Austria.
  • Podhornik A; Division of Cell and Developmental Biology, Center for Anatomy and Cell Biology, Medical University of Vienna, Vienna, Austria.
  • Kothmayer M; Division of Cell and Developmental Biology, Center for Anatomy and Cell Biology, Medical University of Vienna, Vienna, Austria.
  • Reichart U; Division of Cell and Developmental Biology, Center for Anatomy and Cell Biology, Medical University of Vienna, Vienna, Austria.
  • Glösmann M; VetCORE - Facility for Research, University of Veterinary Medicine Vienna, Vienna, Austria.
  • Tamir I; VetCORE - Facility for Research, University of Veterinary Medicine Vienna, Vienna, Austria.
  • Mildner M; Campus Science Support Facilities GmbH, Vienna, Austria.
  • Sheibani-Tezerji R; Research Division of Biology and Pathobiology of the Skin, Medical University of Vienna, Vienna, Austria.
  • Kenner L; Ludwig Boltzmann Institute Applied Diagnostics, Vienna, Austria.
  • Petzelbauer P; Unit of Laboratory Animal Pathology, University of Veterinary Medicine, Vienna, Austria.
  • Egger G; Christian Doppler Laboratory for Applied Metabolomics, Vienna, Austria.
  • Sibilia M; Department of Pathology, Medical University of Vienna, Vienna, Austria.
  • Ablasser A; CBmed GmbH - Center for Biomarker Research in Medicine, Graz, Austria.
  • Seiser C; Skin and Endothelium Research Division, Department of Dermatology, Medical University of Vienna, Vienna, Austria.
EMBO J ; 40(22): e108234, 2021 11 15.
Article in En | MEDLINE | ID: mdl-34586646

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: DNA Methylation / Dermatitis / Epidermis / Nucleotidyltransferases Limits: Animals / Humans Language: En Journal: EMBO J Year: 2021 Document type: Article Affiliation country: Austria

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: DNA Methylation / Dermatitis / Epidermis / Nucleotidyltransferases Limits: Animals / Humans Language: En Journal: EMBO J Year: 2021 Document type: Article Affiliation country: Austria