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TLR4 deletion increases basal energy expenditure and attenuates heart apoptosis and ER stress but mitigates the training-induced cardiac function and performance improvement.
de Vicente, Larissa G; Muñoz, Vitor R; Pinto, Ana P; Rovina, Rafael L; da Rocha, Alisson L; Marafon, Bruno B; Tavares, Maria Eduarda de A; Teixeira, Giovana R; Ferrari, Gustavo D; Alberici, Luciane C; Frantz, Fabiani G; Simabuco, Fernando M; Ropelle, Eduardo R; de Moura, Leandro P; Cintra, Dennys E; Pauli, José R; da Silva, Adelino S R.
Affiliation
  • de Vicente LG; Postgraduate Program in Rehabilitation and Functional Performance, Ribeirão Preto Medical School, University of São Paulo (USP), Ribeirão Preto, São Paulo, Brazil.
  • Muñoz VR; Laboratory of Molecular Biology of Exercise (LaBMEx), School of Applied Sciences, University of Campinas (UNICAMP), Limeira, São Paulo, Brazil.
  • Pinto AP; Postgraduate Program in Rehabilitation and Functional Performance, Ribeirão Preto Medical School, University of São Paulo (USP), Ribeirão Preto, São Paulo, Brazil.
  • Rovina RL; School of Physical Education and Sport of Ribeirão Preto, University of São Paulo (USP), Ribeirão Preto, São Paulo, Brazil.
  • da Rocha AL; Postgraduate Program in Rehabilitation and Functional Performance, Ribeirão Preto Medical School, University of São Paulo (USP), Ribeirão Preto, São Paulo, Brazil.
  • Marafon BB; School of Physical Education and Sport of Ribeirão Preto, University of São Paulo (USP), Ribeirão Preto, São Paulo, Brazil.
  • Tavares MEA; Multicenter Graduate Program in Physiological Sciences, SBFis, São Paulo State University (UNESP), Araçatuba, São Paulo, Brazil.
  • Teixeira GR; Multicenter Graduate Program in Physiological Sciences, SBFis, São Paulo State University (UNESP), Araçatuba, São Paulo, Brazil; Department of Physical Education, State University of São Paulo (UNESP), Presidente Prudente, São Paulo, Brazil.
  • Ferrari GD; Department of Biomolecular Sciences, School of Pharmaceutical Sciences of Ribeirao Preto, University of Sao Paulo-FCFRP USP, Ribeirao Preto, Sao Paulo, Brazil.
  • Alberici LC; Department of Biomolecular Sciences, School of Pharmaceutical Sciences of Ribeirao Preto, University of Sao Paulo-FCFRP USP, Ribeirao Preto, Sao Paulo, Brazil.
  • Frantz FG; School of Pharmaceutical Sciences of Ribeirão Preto, Department of Clinical, Toxicological, and Bromatological Analysis, University of São Paulo (USP), Ribeirão Preto, São Paulo, Brazil.
  • Simabuco FM; Laboratory of Molecular Biology of Exercise (LaBMEx), School of Applied Sciences, University of Campinas (UNICAMP), Limeira, São Paulo, Brazil.
  • Ropelle ER; Laboratory of Molecular Biology of Exercise (LaBMEx), School of Applied Sciences, University of Campinas (UNICAMP), Limeira, São Paulo, Brazil.
  • de Moura LP; Laboratory of Molecular Biology of Exercise (LaBMEx), School of Applied Sciences, University of Campinas (UNICAMP), Limeira, São Paulo, Brazil.
  • Cintra DE; Laboratory of Molecular Biology of Exercise (LaBMEx), School of Applied Sciences, University of Campinas (UNICAMP), Limeira, São Paulo, Brazil.
  • Pauli JR; Laboratory of Molecular Biology of Exercise (LaBMEx), School of Applied Sciences, University of Campinas (UNICAMP), Limeira, São Paulo, Brazil.
  • da Silva ASR; Postgraduate Program in Rehabilitation and Functional Performance, Ribeirão Preto Medical School, University of São Paulo (USP), Ribeirão Preto, São Paulo, Brazil; School of Physical Education and Sport of Ribeirão Preto, University of São Paulo (USP), Ribeirão Preto, São Paulo, Brazil. Electronic a
Life Sci ; 285: 119988, 2021 Nov 15.
Article in En | MEDLINE | ID: mdl-34592238
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Physical Conditioning, Animal / Ventricular Function / Apoptosis / Energy Metabolism / Toll-Like Receptor 4 / Endoplasmic Reticulum Stress / Heart Ventricles Type of study: Health_economic_evaluation / Prognostic_studies Limits: Animals Language: En Journal: Life Sci Year: 2021 Document type: Article Affiliation country: Brasil Country of publication: Países Bajos
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Physical Conditioning, Animal / Ventricular Function / Apoptosis / Energy Metabolism / Toll-Like Receptor 4 / Endoplasmic Reticulum Stress / Heart Ventricles Type of study: Health_economic_evaluation / Prognostic_studies Limits: Animals Language: En Journal: Life Sci Year: 2021 Document type: Article Affiliation country: Brasil Country of publication: Países Bajos