Approaches to Establishing Tolerance in Immune Mediated Diseases.
Front Immunol
; 12: 744804, 2021.
Article
in En
| MEDLINE
| ID: mdl-34616405
ABSTRACT
The development of rational approaches to restore immune tolerance requires an iterative approach that builds on past success and utilizes new mechanistic insights into immune-mediated pathologies. This article will review concepts that have evolved from the clinical trial experience of the Immune Tolerance Network, with an emphasis on lessons learned from the innovative mechanistic studies conducted for these trials and new strategies under development for induction of tolerance.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Immune Tolerance
/
Immune System Diseases
Type of study:
Clinical_trials
Limits:
Humans
Language:
En
Journal:
Front Immunol
Year:
2021
Document type:
Article
Affiliation country:
Estados Unidos