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Viral genome wide association study identifies novel hepatitis C virus polymorphisms associated with sofosbuvir treatment failure.
Smith, David A; Fernandez-Antunez, Carlota; Magri, Andrea; Bowden, Rory; Chaturvedi, Nimisha; Fellay, Jacques; McLauchlan, John; Foster, Graham R; Irving, William L; Simmonds, Peter; Pedergnana, Vincent; Ramirez, Santseharay; Bukh, Jens; Barnes, Eleanor; Ansari, M Azim.
Affiliation
  • Smith DA; Peter Medawar Building for Pathogen Research, Nuffield Department of Medicine, University of Oxford, Oxford, OX3 1SY, UK.
  • Fernandez-Antunez C; Copenhagen Hepatitis C Program (CO-HEP), Department of Infectious Diseases, Hvidovre Hospital and Department of Immunology and Microbiology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
  • Magri A; Peter Medawar Building for Pathogen Research, Nuffield Department of Medicine, University of Oxford, Oxford, OX3 1SY, UK.
  • Bowden R; Wellcome Centre for Human Genetics, University of Oxford, Oxford, OX3 7BN, UK.
  • Chaturvedi N; School of Life Sciences, École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.
  • Fellay J; School of Life Sciences, École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.
  • McLauchlan J; Precision Medicine Unit, University Hospital and University of Lausanne, Lausanne, Switzerland.
  • Foster GR; Swiss Institute of Bioinformatics, Lausanne, Switzerland.
  • Irving WL; MRC-University of Glasgow Centre for Virus Research, Glasgow, G61 1QH, UK.
  • Simmonds P; NIHR Nottingham Biomedical Research Centre, Nottingham University Hospitals NHS Trust and the University of Nottingham, Nottingham, UK.
  • Ramirez S; Peter Medawar Building for Pathogen Research, Nuffield Department of Medicine, University of Oxford, Oxford, OX3 1SY, UK.
  • Bukh J; MIVEGEC, Université de Montpellier, CNRS, 34000, Montpellier, France.
  • Barnes E; Copenhagen Hepatitis C Program (CO-HEP), Department of Infectious Diseases, Hvidovre Hospital and Department of Immunology and Microbiology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
  • Ansari MA; Copenhagen Hepatitis C Program (CO-HEP), Department of Infectious Diseases, Hvidovre Hospital and Department of Immunology and Microbiology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Nat Commun ; 12(1): 6105, 2021 10 20.
Article in En | MEDLINE | ID: mdl-34671027
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Antiviral Agents / Genome, Viral / Hepacivirus / Hepatitis C, Chronic / Sofosbuvir Type of study: Risk_factors_studies Limits: Humans Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2021 Document type: Article Affiliation country: Reino Unido Country of publication: Reino Unido
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Antiviral Agents / Genome, Viral / Hepacivirus / Hepatitis C, Chronic / Sofosbuvir Type of study: Risk_factors_studies Limits: Humans Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2021 Document type: Article Affiliation country: Reino Unido Country of publication: Reino Unido