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Effect of chirality on the anticancer activity of Pt(II) and Pt(IV) complexes containing 1R,2R and 1S,2S enantiomers of the trans-1,2-diamino-4-cyclohexene ligand (DACHEX), an analogue of diaminocyclohexane used in oxaliplatin.
Papadia, Paride; Barbanente, Alessandra; Ditaranto, Nicoletta; Hoeschele, James D; Natile, Giovanni; Marzano, Cristina; Gandin, Valentina; Margiotta, Nicola.
Affiliation
  • Papadia P; Department of Biological and Environmental Sciences and Technologies (DiSTeBA), University of Salento, 73100 Lecce, Italy.
  • Barbanente A; Department of Chemistry, University of Bari Aldo Moro, Via E. Orabona 4, 70125 Bari, Italy. nicola.margiotta@uniba.it.
  • Ditaranto N; Department of Chemistry, University of Bari Aldo Moro, Via E. Orabona 4, 70125 Bari, Italy. nicola.margiotta@uniba.it.
  • Hoeschele JD; CSGI (Consorzio per lo Sviluppo dei sistemi a Grande Interfase) - Bari Unit, c/o Department of Chemistry, University of Bari Aldo Moro, Via E. Orabona 4, 70125 Bari, Italy.
  • Natile G; Department of Chemistry, Eastern Michigan University, 48197 Ypsilanti, MI, USA.
  • Marzano C; Department of Chemistry, University of Bari Aldo Moro, Via E. Orabona 4, 70125 Bari, Italy. nicola.margiotta@uniba.it.
  • Gandin V; Dipartimento di Scienze del Farmaco, Università di Padova, Via Marzolo 5, 35131, Padova, Italy.
  • Margiotta N; Dipartimento di Scienze del Farmaco, Università di Padova, Via Marzolo 5, 35131, Padova, Italy.
Dalton Trans ; 50(43): 15655-15668, 2021 Nov 09.
Article in En | MEDLINE | ID: mdl-34673864
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Oxaliplatin Language: En Journal: Dalton Trans Journal subject: QUIMICA Year: 2021 Document type: Article Affiliation country: Italia Country of publication: Reino Unido
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Oxaliplatin Language: En Journal: Dalton Trans Journal subject: QUIMICA Year: 2021 Document type: Article Affiliation country: Italia Country of publication: Reino Unido