Sulbactam improves binding property and uptake capacity of glutamate transporter-1 and decreases glutamate concentration in the CA1 region of hippocampus of global brain ischemic rats.

Gu, Wei-Wei; Cui, Xin; Liu, Li-Zhe; Zhang, Min; Li, Wen-Bin; Xian, Xiao-Hui

Gu, Wei-Wei; Cui, Xin; Liu, Li-Zhe; Zhang, Min; Li, Wen-Bin; Xian, Xiao-Hui.

Affiliation

Gu WW; Department of Pathophysiology, Neuroscience Research Center, Hebei Medical University, 361 Zhongshan East Road, Shijiazhuang, Hebei, 050017, People's Republic of China.
Cui X; Hebei Key Laboratory of Critical Disease Mechanism and Intervention, Hebei Medical University, Shijiazhuang, Hebei, People's Republic of China.
Liu LZ; Comprehensive Medical Laboratory of the Third Hospital, Hebei Medical University, Shijiazhuang, Hebei, People's Republic of China.
Zhang M; Yanjing Medical College of Capital Medical University, Beijing, People's Republic of China.
Li WB; Department of Pathophysiology, Neuroscience Research Center, Hebei Medical University, 361 Zhongshan East Road, Shijiazhuang, Hebei, 050017, People's Republic of China.
Xian XH; Hebei Key Laboratory of Critical Disease Mechanism and Intervention, Hebei Medical University, Shijiazhuang, Hebei, People's Republic of China.

Amino Acids ; 53(11): 1649-1661, 2021 Nov.

Article in En | MEDLINE | ID: mdl-34716803

Subject(s)
Key words

Binding property; Glutamate concentration; Glutamate transporter-1; Rats; Sulbactam; Uptake capacity

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Sulbactam / Brain Ischemia / Glutamic Acid / Excitatory Amino Acid Transporter 2 / CA1 Region, Hippocampal Limits: Animals / Humans / Male Language: En Journal: Amino Acids Journal subject: BIOQUIMICA Year: 2021 Document type: Article Country of publication: Austria

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