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Concordance of BRCA mutation detection in tumor versus blood, and frequency of bi-allelic loss of BRCA in tumors from patients in the phase III SOLO2 trial.
Hodgson, Darren R; Brown, Jessica S; Dearden, Simon P; Lai, Zhongwu; Elks, Cathy E; Milenkova, Tsveta; Dougherty, Brian A; Lanchbury, Jerry S; Perry, Michael; Timms, Kirsten M; Harrington, Elizabeth A; Barrett, J Carl; Leary, Alexandra; Pujade-Lauraine, Eric.
Affiliation
  • Hodgson DR; Translational Medicine, Oncology R+D, Research and Early Development, AstraZeneca, Boston, MA, USA.
  • Brown JS; Translational Medicine, Oncology R+D, Research and Early Development, AstraZeneca, Cambridge, United Kingdom. Electronic address: jessica.brown1@astrazeneca.com.
  • Dearden SP; Precision Medicine and Biosamples, R&D Oncology, AstraZeneca, Cambridge, United Kingdom.
  • Lai Z; Translational Medicine, Oncology R+D, Research and Early Development, AstraZeneca, Boston, MA, USA.
  • Elks CE; Precision Medicine and Biosamples, R&D Oncology, AstraZeneca, Cambridge, United Kingdom.
  • Milenkova T; AstraZeneca, Cambridge, United Kingdom.
  • Dougherty BA; Translational Medicine, Oncology R+D, Research and Early Development, AstraZeneca, Boston, MA, USA.
  • Lanchbury JS; Myriad Genetics, Salt Lake City, UT, USA.
  • Perry M; Myriad Genetics, Salt Lake City, UT, USA.
  • Timms KM; Myriad Genetics, Salt Lake City, UT, USA.
  • Harrington EA; Translational Medicine, Oncology R+D, Research and Early Development, AstraZeneca, Cambridge, United Kingdom.
  • Barrett JC; Translational Medicine, Oncology R+D, Research and Early Development, AstraZeneca, Boston, MA, USA.
  • Leary A; Department of Medicine and INSERM U981, Université Paris Saclay and Institut Gustave-Roussy, Villejuif, France.
  • Pujade-Lauraine E; Medical Oncology Department, Université Paris Descartes, AP-HP, Paris, France.
Gynecol Oncol ; 163(3): 563-568, 2021 12.
Article in En | MEDLINE | ID: mdl-34742578
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Ovarian Neoplasms / Germ-Line Mutation / Loss of Heterozygosity / BRCA2 Protein / Ubiquitin-Protein Ligases Type of study: Clinical_trials / Diagnostic_studies Limits: Female / Humans Language: En Journal: Gynecol Oncol Year: 2021 Document type: Article Affiliation country: Estados Unidos
Fulltext
Add to My VHL
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Ovarian Neoplasms / Germ-Line Mutation / Loss of Heterozygosity / BRCA2 Protein / Ubiquitin-Protein Ligases Type of study: Clinical_trials / Diagnostic_studies Limits: Female / Humans Language: En Journal: Gynecol Oncol Year: 2021 Document type: Article Affiliation country: Estados Unidos