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SPICA: Swiss portal for immune cell analysis.
Andreatta, Massimo; David, Fabrice P A; Iseli, Christian; Guex, Nicolas; Carmona, Santiago J.
Affiliation
  • Andreatta M; Ludwig Institute for Cancer Research, Lausanne Branch, and Department of Oncology, CHUV and University of Lausanne, Epalinges 1066, Switzerland.
  • David FPA; Swiss Institute of Bioinformatics, Lausanne, Switzerland.
  • Iseli C; Bioinformatics Competence Center, École Polytechnique Fédérale de Lausanne, CH-1015 Lausanne, Switzerland.
  • Guex N; Bioinformatics Competence Center, École Polytechnique Fédérale de Lausanne, CH-1015 Lausanne, Switzerland.
  • Carmona SJ; Bioinformatics Competence Center, University of Lausanne, CH-1015 Lausanne, Switzerland.
Nucleic Acids Res ; 50(D1): D1109-D1114, 2022 01 07.
Article in En | MEDLINE | ID: mdl-34747477
ABSTRACT
Single-cell transcriptomics allows the study of immune cell heterogeneity at an unprecedented level of resolution. The Swiss portal for immune cell analysis (SPICA) is a web resource dedicated to the exploration and analysis of single-cell RNA-seq data of immune cells. In contrast to other single-cell databases, SPICA hosts curated, cell type-specific reference atlases that describe immune cell states at high resolution, and published single-cell datasets analysed in the context of these atlases. Additionally, users can privately analyse their own data in the context of existing atlases and contribute to the SPICA database. SPICA is available at https//spica.unil.ch.
Subject(s)

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Databases, Genetic / Transcriptome Limits: Humans Language: En Journal: Nucleic Acids Res Year: 2022 Document type: Article Affiliation country: Suiza

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Databases, Genetic / Transcriptome Limits: Humans Language: En Journal: Nucleic Acids Res Year: 2022 Document type: Article Affiliation country: Suiza