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An efficient chemical screening method for structure-based inhibitors to nucleic acid enzymes targeting the DNA repair-replication interface and SARS CoV-2.
Moiani, Davide; Link, Todd M; Brosey, Chris A; Katsonis, Panagiotis; Lichtarge, Olivier; Kim, Youngchang; Joachimiak, Andrzej; Ma, Zhijun; Kim, In-Kwon; Ahmed, Zamal; Jones, Darin E; Tsutakawa, Susan E; Tainer, John A.
Affiliation
  • Moiani D; Department of Cancer Biology, University of Texas MD Anderson Cancer Center, Houston, TX, United States; Department of Molecular & Cellular Oncology, University of Texas MD Anderson Cancer Center, Houston, TX, United States.
  • Link TM; Department of Cancer Biology, University of Texas MD Anderson Cancer Center, Houston, TX, United States; Department of Molecular & Cellular Oncology, University of Texas MD Anderson Cancer Center, Houston, TX, United States.
  • Brosey CA; Department of Cancer Biology, University of Texas MD Anderson Cancer Center, Houston, TX, United States; Department of Molecular & Cellular Oncology, University of Texas MD Anderson Cancer Center, Houston, TX, United States.
  • Katsonis P; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, United States.
  • Lichtarge O; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, United States.
  • Kim Y; Center for Structural Genomics of Infectious Diseases, Consortium for Advanced Science and Engineering, University of Chicago, Chicago, IL, United States; Department of Biochemistry and Molecular Biology, University of Chicago, Chicago, IL, United States.
  • Joachimiak A; Center for Structural Genomics of Infectious Diseases, Consortium for Advanced Science and Engineering, University of Chicago, Chicago, IL, United States; Department of Biochemistry and Molecular Biology, University of Chicago, Chicago, IL, United States.
  • Ma Z; Department of Chemistry, University of Cincinnati, Cincinnati, OH, United States.
  • Kim IK; Department of Chemistry, University of Cincinnati, Cincinnati, OH, United States.
  • Ahmed Z; Department of Cancer Biology, University of Texas MD Anderson Cancer Center, Houston, TX, United States; Department of Molecular & Cellular Oncology, University of Texas MD Anderson Cancer Center, Houston, TX, United States.
  • Jones DE; Department of Pharmaceutical Sciences, The University of Arkansas for Medical Sciences, Little Rock, AR, United States.
  • Tsutakawa SE; Biophysics and Integrated Bioimaging, Lawrence Berkeley National Laboratory, Berkeley, CA, United States. Electronic address: setsutakawa@lbl.gov.
  • Tainer JA; Department of Cancer Biology, University of Texas MD Anderson Cancer Center, Houston, TX, United States; Department of Molecular & Cellular Oncology, University of Texas MD Anderson Cancer Center, Houston, TX, United States; Biophysics and Integrated Bioimaging, Lawrence Berkeley National Labora
Methods Enzymol ; 661: 407-431, 2021.
Article in En | MEDLINE | ID: mdl-34776222
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Nucleic Acids / Severe Acute Respiratory Syndrome / COVID-19 Type of study: Diagnostic_studies / Screening_studies Limits: Humans Language: En Journal: Methods Enzymol Year: 2021 Document type: Article Affiliation country: Estados Unidos Country of publication: Estados Unidos
Fulltext
Add to My VHL
Print
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Nucleic Acids / Severe Acute Respiratory Syndrome / COVID-19 Type of study: Diagnostic_studies / Screening_studies Limits: Humans Language: En Journal: Methods Enzymol Year: 2021 Document type: Article Affiliation country: Estados Unidos Country of publication: Estados Unidos